Neurology Flashcards
Dose of Ativan?
0.1mg/kg
What would happen to the FVC for GBS? and what test are used to test for GBS? how is it presented?
Decrease/CSF first then electromyography
Days or weeks after infection/usually with autonomic dysfunction (tachy/arrhythmia/urinary retention)
What kind of protein would you find in the CSF of Creutzfeldt-Jakob disease?
14-3-3 protein
Weber and Benedikt syndrome
Posterior cerebral artery—>CN III palsy
Young ppl have stroke, what to look for?
Hypercoagulable state/vasculitis
Pt has a stroke while on aspirin, come to hospital more than 3 hours, what to add?
Dipyridamole
Asymptomatic aneurysm under 5mm?
Leave it alone
Pt has a stroke with increased ICP comes in 5 hours after the onset, what to do?
Permissive HTN to perfuse the brain
Straight leg raise is testing for myelopathy or radiculopathy
Radiculopathy
What to give with acute myelopathy?
Dexamethasone
IV drug user with fever and back pain?
Epidural abscess
GBS has any sensory loss?
No
Age onset for frontaltemporal dementia
40-60
Symptoms of medial and lateral cerebella lesions?
Medial—>vertigo and nystagmus
Lateral—>ataxia/dizziness/sway to side of lesion
Signs of spinal cord compression?
Lower back pain at night/bilateral weakness and sensory loss
Dejerine-Roussy syndrome?
Thalamic pain syndrome—>severe burning pain follow thalamic stroke
Mononeuritis multiplex
asymmetric neuropathy with multiple nerves
associated with vasculitis
Low complement/purpura
Wallenberg syndrome
Lateral medulla infarction (PICA or vertebral)
Ipsilateral Horner/hoarseness/dysphagia
Ipsilateral loss of pain and temp on face and contra on limbs (similar to PCA)
Dizziness and unsteadiness
Hyperostosis of skull, what tumor?
Meningioma
Language deficits of Alzheimer’s
Transcortical sensory aphasia—>can’t understand complex linguistic structure
Decrease in fluency
Location of Lewy bodies
Intracytoplasmic inclusion bodies
Long term tx for MS?
Interferon beta/glatiramer
optic neuritis
Demylination of optic nerve Unilateral loss of vision/central vision loss or any other kind eye pain with movement Change in color perception MS/lupus Tx--->IV steroid
Vertebrobasilar artery occlusion
Vertigo (dizziness)
Straight leg raise test for?
Herniated disc
Vegetarian/bowel disease, think?
Subacute combined degeneration
UMN lesion/mental change
Lambert Eaton
Proximal muscle weakness/ptosis/diplopia
Meds for Meniere disease
Meclizine (1st gen antihistamine) and scopolamine (anti M)
Low salt diet/diuretics
Complication of CSF leak
S. pneumoniae meningitis
Tethered cord syndrome adult
Back/leg pain/scoliosis
Cause of benign paroxysmal positional vertigo
Otolith in semicircular canal
Cavernous sinus thrombosis?
Can lead to?
fever/retro-orbital headache/swollen protruding eye/CN346 palsy
lead to intracranial HTN (papilledema)
Midbrain stroke?
Ipsilateral CN III palsy/ataxia
Contra weakness
Subacute combined generation symptoms
progressive symmetrical polyneuropathy more in legs than arms
loss of proprioception—>gait ataxia
UMN signs
Cholesteatoma
Overgrowth of keratinizing squamous epithelium
Ear discharge
White plaque on tympanic membrane
Anterior cord syndrome caused by?
Burst fracture of vertebra
What to give with acute migraine pt with nausea and vomiting?
IV antiemetics (chlorpromazine/prochlorperazine/metoclopramide)
Pure motor stroke, what kind of stroke is it?
Lacunar stroke of posterior limb of internal capsule from HTN
Tx for GBS?
IV immunogloblin and plasmapheresis
Difference between seizure and syncope
Syncope has prodrome like lightheadness/weak pulses
Seizure has aura (vision usually)
Sleep deprivation can cause seizure
What is preserved with brain dead pt?
Deep tendon reflexes
Headache leaning forward/cough/Valsalva
increase ICP
Chronic alcohol abuser
Intention tremor (cerebellar dysfunction)
Otosclerosis
Hereditary conductive hearing loss in late teens
Ankylosis of stapedial foot plate
How do you know it is spondylosis? use what to image?
Limited ROM/Spurling test/Lhermitte sign
X ray
Pt is on anticoagulation, brain bleed, stop anticoagulation, what to do next?
IVC filter to prevent emboli from stopping the anticoagulation
Tx for Huntington
Tetrabenazine
Tx for intact functional state below or over 60 of age of Parkinson pt
anticholinergic for movement
>60 —>amantadine
Parkinson + vertical gaze palsy
Parkinson + ataxia
Parkinson + orthostatic HoTN
Progressive supranuclear palsy (no tremor)
Olivopontocerebellar atrophy
Shy-Drager syndrome
What drug slow the progression of Alzheimer’s disease?
Memantine
Does steroid help with GBS?
NOOOOOOOOOO
Steroid for ICH?
NOOOOO
Tx for Tourette’s
Clonidine
1st gen antipsychotic
Antipsychotic makes it worse
Lewy body dementia
What drug is for secondary progressive MS?
Mitoxantrone
Tx for DMD?
Steroid
NF1, you see?
Cafe au lait
Cutenaous neurofibroma
Lisch Nodules
Freckling
Tuberous sclerosis, you see?
epilepsy
renal angiomyolipoma
rhadomyoma of the heart
Capillary angiomatoses of pia matter?
Sturge weber syndrome
Tx for vasvagal syncope
Beta blocker/disopyramide
Difference between partial/generalized
simple/complex
Partial—>one part of brain
Generalized—>entire (convulsive)
Simple—>no LOC
Complex—>LOC
Is absence seizure partial or generalized seizure?
Generalized
MOA of metoclopramide
D2 antagonist (anti psychotic)
Kernig and Brudinski sign?
Kernig-flex thigh 90 degree. Extend of leg cause pain. Inflammation of hamstring
Brudinski-neck flexion causes leg flexion
Both indicate meningitis
What besides GBS causes autonomic dysfunction? And how do you test for it?
Botulism
Mouse bioassay
Central cord syndrome
Hyperextension
Affect spinothalamic and corticalspinal tract
TIA time limit
24 hours