Neurology Flashcards
What is a transient ischaemic attack?
transient episode of neurological dysfunction
caused by focal brain, spinal cord, or retinal ischaemia
without acute infarction
What are the risk factors fro a TIA?
Older age
Male
Previous TIA
Smoking
Physical inactivity
Hypertension
AF
Carotid artery disease
Hyperlipidaemia
Diabetes
How does a TIA present?
Sudden onset of+ resolves within an hour:
Unilateral weakness or sensory loss
Aphasia or dysarthria
Ataxia, vertigo or loss of balance
Visual problems
How are TIAs investigated?
MRI head
Carotid Doppler
What medication given in a TIA?
Aspirin 300mg
What is given to prevent TIAs?
Clopidogrel (if can’t tolerate - aspirin + dipyridamole)
Statin (atorvastatin)
Carotid endarectomy (>70% carotid stenosis)
What is a stroke?
Sudden onset neurological deficit
Due to ishaemic or haemorrhagic compromise in the blood supply to the brain
Lasts more than 24 hours/evidence of infarction
What is an ischaemic stroke?
Vascular occlusion or stenosis causing inadequate blood flow to parts of the brain
What is a haemorrhagic stroke?
Vascular rupture of a vessel in the brain causing haemorrhage
What are the identification tools used to identify ischaemic strokes?
FAST (community)
ROSIER score (hospital)
How is an ischaemic stroke investigated?
Blood glucose (hypoglycaemia?)
Non-contrast CT head (haemorrhage?)
MRI (shows vascular territory effected)
How is an ischaemic stroke managed?
Thrombolysis with ateplase
Mechanical thrombectomy
Aspirin 300mg daily for 2 weeks
No driving for 1 month
What are the contraindications for thrombolysis with ateplase?
Active internal bleeding
Recent haemorrhage
Recent surgery
Recent head injury
Bleeding disorder/coagulation
Stroke < 3 months
Sever hypertension
How are strokes classified?
Bamford/oxford stroke classification
What is the criteria for a total anterior circulation stroke (TACS)?
All 3 of:
- unilateral weakness (+/- sensory deficit) of the face, arm and leg
- homonymous hemianopia
- higher cerebral dysfunction (dysphasia, visuospatial disorder)