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RACP Paediatric Exam > Neurology > Flashcards

Neurology Flashcards

1
Q

What AED is associated with pancreatitis?

A

Valproate

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2
Q

What AED is associated with hair loss?

A

Valproate

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3
Q

What AED is associated with liver failure?

A

Valproate

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4
Q

What AEDs are associated with rash? (4)

A

carbamazepine, phenobarb, lamotrigine, phenytoin

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5
Q

What AED is associated with retinopathy?

A

Vigabatrin

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6
Q

What AED is associated with psychosis?

A

Vigabatrin

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7
Q

What AED is associated with gum hypertrophy?

A

Phenytoin

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8
Q

What AED is associated with hirsuitism?

A

Phenytoin

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9
Q

What AED is associated with osteoporosis?

A

Phenytoin

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10
Q

What AED is associated with serum sickness?

A

Phenytoin

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11
Q

What AED increases lamotrigine cocentration?

A

Valproate

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12
Q

What AED is associated with SJS?

A

Lamotrigine

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13
Q

What AEDs are associated with hyponatraemia? (2)

A

Oxcarbazepine, carbamazepine

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14
Q

What AED is associated with leukopaenia?

A

CBZ

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15
Q

What AED is associated with increased secretions?

A

Benzos

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16
Q

What AED is associated with nephrolithiasis?

A

Topiramate

17
Q

What AED is associated with metabolic acidosis?

A

Topiramate

18
Q

Which AED is contraindicated in glaucoma?

19
Q

Which drugs decrease the half life of lamotrigine? (4)

A 
Drug inducers reduce the half-life of LTG  
Carbamazepine 
Phenytoin
Combined oral contraceptive pill 
Rifampicin
20
Q

Which drug increases the half life of lamotrigine?

21
Q

What AED can precipitate CBZ side effects?

A

Lamotrigine

22
Q

What medications inhibit CBZ metabolism and cause elevated levels? (5)

A 
Macrolide abx
Metronidazole
Certain antidepressants
Verapamil
Diltiazem
23
Q

Which AED causes increased MCV?

How?

A
  • Phenytoin

- Decreased folate metabolism

RACP Paediatric Exam (4 decks)

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