Neurology 1 Flashcards
-Brain Lesions-CVA
Visual problem in pituitary tumor compressing optic chiasm (10x)
bitemporal hemianopsia
Unsteady gait, appendicular ataxia in LE only, normal eye movement. Walks with lurching broad-based gait. Dx? (8x)
Cerebellar degeneration (alcoholic)
66y c/o frequent falls, several month h/o of anxiety, unwillingness to leave home. Exam: mild impairment of vertical gaze on smooth pursuit/saccades, mild axial rigiditiy & minimal rigidity of UE, mild slowness of finger tapping, hand opening & wrist opposition. Posture nml. Gait tentative/awkward, but w/o shuffling, ataxia, tremor. Pt slow in rising from chair. Most likely dx (8x)
Progressive supranuclear palsy
Severe occipital h/a, BL papilledema and no other abnl. Chronic acne treated wtih isotretinoin. LP elevated opening pressure with no cells, 62mg/dL glucose, 22mg/rL protein. Normal CT. Dx? (7x)
pseudotumor cerebri
79y deteriorating mental state over 3-wk period has an exaggerated startle repsonse with violent myoclonus that is elicited by turning on the room lights, speaking loudly, or touching the pt. Myoclonic jerks also seen. Dx: (5x)
Spongiform encephalopathy
Slowly progressive gait disorder, followed by impairment of mental function, and sphincteric incontinence. No papilledema or h/a reported. Likely dx? (4x)
Normal pressure hydrocephalus
65y fell several times past 6mo. MSE nl. Smooth pursuit, saccadic movements impaired. Worse w/ vertical gaze. Full ROM w/ doll head maneuver. Mild symmetric rigidity/bradykinesia, no tremor. MRI/CSF/labs unremarkable. Dx? (4x)
Progressive Supranuclear Palsy
Acute onset of pain, decr vision in R eye. Colors look faded when viewed through the R eye. On Exam, R afferent pupillary defect and swollen R optic disc. Pt spontaneously recovers over the next 6 wks. Likely to develop later. (4x)
Multiple sclerosis
28y + emotional lability & impulsivity. LFTs elevated. Close relative had similar sx and died at 30y from hepatic failure. Which blood level would dx? (3x)
Ceruloplasmin
Several days of fever + severe h/a presenting to ED b/o generalized seizure. Pt confused and somnolent. Also reported to have been irritable, c/o foul smells. T2 MRI displayed (hyperintensity of L temporal) Dx? (3x)
Herpes encephalitis
9y F has 3m h/o seemingly unprovoked bouts of laughter. Worse when not sleeping well. Pt does not feel happy during these episodes. Started menstruating 6m ago, Tanner stage 4. Dx? (2x)
Hypothalamic hamartoma
5y with 4m h/o morning h/a, vomiting, recent problems with gait, falls, diploplia (2x)
Medulloblastoma
70y + flaccid paralysis following severe water intoxication. Develops dysphagia adn dysarthria without other cranial never involvement. Sensory exam limited but grossly normal, DTRs are symmetric, cognition intact. Likely Dx (2x)
Central pontine myelinolysis
Young adult gained 70lb in last year c/o daily severe h/a sometimes associated with graying of vision. Papilledema present. CT and MRI brain shows smaller ventricles than normal. Goal of rx (2x)
Prevent blindness
Superior homonymous quandrantic defects in the visual fields result from lesions to which of the following structures? (2x)
Temporal optic radiations
Tremor with freq of ~3Hz, irregular amplitude, most evident towards the end of reaching movements. Dx? (2x)
cerebellar tumor
acute onset of fever, sore throat, diplopia & dysarthria. Exam reveals inflamed throat, L adductor nerve palsy w/ impairment of vertical pursuit, diffuse hyperreflexia w/ bilateral clonus, lower ext spasticity, & mild R hemiparesis. CT uninformative. Spinal fluid has protein 24, 10 mononuclear cells, glucose 70. Dx? (2x)
multiple sclerosis
Which is most reliable CSF finding for pt with multiple sclerosis in chronic phase of dz? (2x)
presence of monoclonal bands
Benign intracranial HTN etiology (2x)
hypervitaminosis A
Gait abnl, slow mvmt, asymmetric UE rigidity. Difficulty in voluntary vertical upward/downward gaze. Slowness/rigidity improved slightly with levodopa. Later has problems with horizontal & vertical gaze. Oculocephalic reflexes nl. Involuntary saccades. Dx? (2x)
Progressive supranuclear palsy
Pt presents with personality changes, cognitive difficulties, affective lability, and olfactory and gustatory hallucinations. The most likely medical cause of this presentation is (2x)
Herpes simplex virus (HSV) infection
What condition is a forerunniner of Multiple sclerosis? (2x)
transverse myelitis
Location of characteristic lesions seen in CT scans of pt with carbon monoxide poisoning associated comas (2x)
Globus pallidus
43yo newly w/ AIDS. Pt has inc social withdrawal and irritability over several weeks. Can’t remember phone number, unable to do chores, appears distracted. Mild R hemiparesis, L limb ataxia, bilateral visual field defects. LP normal. T2 scan shown. What is dx? (2x)
Progressive multifocal leukoencephalitis