neurological emergencies Flashcards
can alcohol withdrawal cause a seizure
yes
rescue therapy for seizure
buccal midazolam - rohipnole ( date rape)
rectal diazepam
IV lorazepam ( diazepam )
status epilepticus defintion
over 5 mins of continuous seizure
or over 3 discrete seizures between which there is an incomplete recovery of consciousness
causes of status elipticus
structual brain injury
AED non compliance
withdrawal seizures
metabolic abnormalities
overdose of medication
Ix for status epilepticus
IV acces
glcuse abd urea creatienn LFT electrolytes crp fbc and clotting and anticovulsant drug levels
CXR for aspriation
CT head if no previosu history
PMH and drug use
LP IF CNS infection or inflamation
refractory urgent CT head regardless
provoked seizures causes
( predominately H) stroke
subdural , subarachnoid
HIE
brain abscess
meningitis or encephaltiis
neoplasma
vascular malforamation
brugada syndrome in seizures -features
is herediatary
porlonged PR
RBBB
st segment raised
tx for brugada
apceamke or defib
mx of long QT
BB
drug induced long QT
antiarrhythmis
certain nosedating antihistamines
macrolide abx
certain psychotropic medications
certain gastric motility agents such as domperidone
1st seziure driving
6 months - 1 years of no drive
HGV 1st
10yr
establish epilepsy driving
need to be seizure free for 12months
withdrawal of tx
time to wean and 6 months
SUDEP
sudden unexplained death in epilepsy
this risk is reduced with anti-convulsants
ix for subarachnoid heamorrhage
Investigation
non-contrast CT head is the first-line investigation of choice
acute blood (hyperdense/bright on CT) is typically distributed in the basal cisterns, sulci and in severe cases the ventricular system.
if CT head is done within 6 hours of symptom onset and is normal
new guidelines suggest not doing a lumbar puncture!!!!!1
consider an alternative diagnosis
if CT head is done more than 6 hours after symptom onset and is normal
do a lumber puncture (LP)
timing wise the LP should be performed at least 12 hours following the onset of symptoms to allow the development of xanthochromia (the result of red blood cell breakdown).
xanthochromia helps to distinguish true SAH from a €˜traumatic tap’ (blood introduced by the LP procedure).
as well as xanthochromia, CSF findings consistent with subarachnoid haemorrhage include a normal or raised opening pressure
if the CT shows evidence of a SAH
referral to neurosurgery
After spontaneous SAH is confirmed, do find cause
CT intracranial angiogram (to identify a vascular lesion e.g. aneurysm or AVM)
+/- digital subtraction angiogram (catheter angiogram)
coital headache - thunderclap headache
features
usually nake
during intercourse in orgasm
sudden severe occipital pain
self limiting
distinguidh grom subarachnoid bleed - spondylotic pain