neurological disorders Flashcards
what are symptoms of Parkinson’s disease?
- body tremors when at rest commonly in hands/fingers
- bradykinesia
- hypokinesia
- akinesia
which symptom of PD manifests as slow movement?
bradykinesia
which symptom of PD manifests as decreased amplitude of movement?
hypokinesia
which symptom of PD manifests as disrupted ability to initiate movement?
akinesia
what causes Parkinson’s disease?
loss of dopamine from the substantia nigra to the basal ganglia
pharmacological treatments for PD include …
L-DOPA which is the precursor of dopamine that is permeable to the blood brain barrier
non-pharmacological treatments for PD include …
deep brain stimulation that targets the subthalamic nucleus and GP internal
what are symptoms of Huntington’s disease?
- sudden jerky, involuntary movements throughout the body
- severe balance/coordination problems
- jerky, rapid eye movements
what causes Huntington’s disease?
inheritance of a single abnormal gene resulting in the degeneration of cells in the basal ganglia
Someone who has Huntington’s disease is experiencing a disruption of dopamine through their …
indirect pathway
what is a seizure?
a strong and brief surge of electrical activity in the brain
type of seizure that is confined to one brain region
focal seizure
type of seizure that starts synchronously across multiple brain regions
primary generalized
type of seizure that starts as focal and then spreads to other areas of the brain
secondary generalized
what are the four stages of a seizure?
- prodrome/aura
- ictal
- post-ictal
- interictal