neurological disorder of the foal Flashcards

1
Q

putative causes for neonatal encephalopathy

A

1/ maladaptation to extra-uterine life (altered neurosteroid/progesterone concentration, HPAA function)
2/ perinatal asphyxia (dystocia, umbulical cord abnomalities, severe maternal disease, placental disease)
3/ metabolic abnormalities (sepsis, kernicterus, electrolyte abnomalities, uremic encephalopathy)

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2
Q

1/ cite 2 neurosteroids
2/interact with which receptor
3/ action

A

1/ progesterone and allopregnanolone
2/ GABA and NMDA
3/ neuroprotective in hypoxic condition

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3
Q

molecule produced in locus ceruleus

A

norepinephrine

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4
Q

maj cause of kernicterus in foals

A

neonatal isoerythrolysis (bili > 19 mg/dL)

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5
Q

icteric CSF can be normal in foals up to 10 days : T/F

A

True

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6
Q

electrolytes abnomalities associated with neurologic signs in foals

A

Na >170 meq/L or <120 meq/L (ataxia, seizure, abnormal mentation)
Hypocalcemia (seizures)

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