neurological disorder of the foal Flashcards
putative causes for neonatal encephalopathy
1/ maladaptation to extra-uterine life (altered neurosteroid/progesterone concentration, HPAA function)
2/ perinatal asphyxia (dystocia, umbulical cord abnomalities, severe maternal disease, placental disease)
3/ metabolic abnormalities (sepsis, kernicterus, electrolyte abnomalities, uremic encephalopathy)
1/ cite 2 neurosteroids
2/interact with which receptor
3/ action
1/ progesterone and allopregnanolone
2/ GABA and NMDA
3/ neuroprotective in hypoxic condition
molecule produced in locus ceruleus
norepinephrine
maj cause of kernicterus in foals
neonatal isoerythrolysis (bili > 19 mg/dL)
icteric CSF can be normal in foals up to 10 days : T/F
True
electrolytes abnomalities associated with neurologic signs in foals
Na >170 meq/L or <120 meq/L (ataxia, seizure, abnormal mentation)
Hypocalcemia (seizures)