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Psychiatry > Neuroleptic malignant syndrome > Flashcards

Neuroleptic malignant syndrome Flashcards

1
Q

What is neuroleptic malignant syndrome?

A

A life-threatening emergency associated with the use of antipsychotics

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2
Q

What type of drugs can neuroleptic malignant syndrome occur with?

A

Typical antipsychotics
Atypical antipsychotics
Withdrawal of dopaminergic drugs (levodopa)

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3
Q

What are the symptoms of neuroleptic malignant syndrome?

A

Pyrexia
Muscle rigidity
Hypertension
Tachycardia
Tachypnoea
Altered mental state
Tremor

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4
Q

What results might be seen on blood tests in neuroleptic malignant syndrome?

A

Raised creatinine kinase
AKI
Leukocytosis
Deranged LFTs
Metabolic acidosis

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5
Q

What is the management of neuroleptic malignant syndrome?

A

Stop antipsychotic
IV fluids
Antipyretics
Muscle relaxant - dantrolene, bromocriptine

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6
Q

What are the risk factors for neuroleptic malignant syndrome?

A

Use of antipsychotics
Withdrawal of parkinsons medication
Depot medication
High dose antipsychotics
Previous episode of NMS

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Psychiatry (23 decks)

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