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Emergency Medicine Block > Neuroleptic malignant Syndrome > Flashcards

Neuroleptic malignant Syndrome Flashcards

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1
Q

What are the symptoms of Neuroleptic Malignant Syndrome?

A

Fever
Confusion
Muscle Rigidity
Sweating
Autonomic Instability
Very high CK levels

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2
Q

What are the causes of death in Neuroleptic Malignant Syndrome?

A

Rhabdomyolysis
Renal Failure
Seizures

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3
Q

Risk Factors for Neuroleptic Malignant Syndrome?

A
  • High potency dopamine antagonists - typical antipsychotics
  • antipsychotic naive
    -high doses
  • young men
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4
Q

What is the treatment for Neuroleptic Malignant Syndrome?

A
  • Referral to A&E
  • Stop antipsychotics
  • Give Benzodiazepines
  • Fluid Resuscitation
  • Reduce Temperature
  • Oxygen
  • Rhabdomyolysis (fluids and sodium bicarbonate to alkalise the urine)
    -Relax muscles - 1st: dantrolene/ lorazepam 2nd: bromocriptine
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5
Q

What is Neuroleptic Malignant Syndrome?

A
  • Rare, life-threatening reaction to antipsychotics
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Emergency Medicine Block (8 decks)

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