Neuroleptic Drugs Flashcards

1
Q

MOA of phenothiazines

A

Blocking of D2 and 5-HT2 receptors

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2
Q

Important phenothiazines

A
Chloropromazine
Prochloroperazine
Thioridazine
Fluphenazine
Trifluoperazine
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3
Q

MOA of butyrophenones

A

Strong D2 receptor blockers

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4
Q

Important butyrophenones

A

Droperidol

Haloperidol

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5
Q

4 classes of EPS

A
  1. Parkinsonian-like effects
  2. Akathesia
  3. Acute dystonias
  4. Tardive dyskinesia
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6
Q

Drug requiring regular monitoring of blood?

A

Clozapine

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7
Q

Partial D2 and 5HT1 receptor agonist as well as a 5-HT2 receptor antagonist that is indicated for the treatment of schizophrenia and bipolar disorder?

A

Aripiprazole

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8
Q

2 classes of typical antipsychotics

A

Phenothiazines

Butyrophenones

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