Neuroleptic Drugs Flashcards
1
Q
MOA of phenothiazines
A
Blocking of D2 and 5-HT2 receptors
2
Q
Important phenothiazines
A
Chloropromazine Prochloroperazine Thioridazine Fluphenazine Trifluoperazine
3
Q
MOA of butyrophenones
A
Strong D2 receptor blockers
4
Q
Important butyrophenones
A
Droperidol
Haloperidol
5
Q
4 classes of EPS
A
- Parkinsonian-like effects
- Akathesia
- Acute dystonias
- Tardive dyskinesia
6
Q
Drug requiring regular monitoring of blood?
A
Clozapine
7
Q
Partial D2 and 5HT1 receptor agonist as well as a 5-HT2 receptor antagonist that is indicated for the treatment of schizophrenia and bipolar disorder?
A
Aripiprazole
8
Q
2 classes of typical antipsychotics
A
Phenothiazines
Butyrophenones