NEUROHISTO Flashcards
Oligodendrocytes
in white matter : myelin sheath formation
in grey matter: closely associated with neuron cell bodies, function as satellite cells
Microglia
immune cells of CNS
phagocytic cells that enlarge and become mobile after injury to CNS
Astrocytes
- regulate composition of intercellular environment and entry of substances into it , provide structural support to neurons
- metabolise neurotransmitters
- mediate exchange of nutrients between metabolites and blood
Schwann cells
- neuroglia in PNS
- myelinates nerve fibres
- provides electrical insulation
- faster conduction of nerve impulses along the axons
Ependymal cells
- epithelial cells lining ventricles
- separate CSF from nervous tissue
Peripheral nerve structure
- comprises bundles of myelinated axons
- surrounded by connective tissue elements
1. epineurium
2. perineurium
3. endoneurium
epineurium
connective tissue surrounding the entire nerve
perineurium
a layer of dense connective tissue around each bundle of axons
endoneurium
thin reticular layer that surrounds each individual nerve fiber and contains schwann cells
structure of peripheral ganglion
- capsulated collections of neuron cell bodies
- contain satellite cells and connective tissue elements along with neurons
axons
nerve fibres that conduct impulses away from the cell body
axons cytoplasm lacks ribo, rer, golgi
dendrites
conduct impulses toward cell body
excitatory synapse
neurotransmitter binds -> Na+ channels in post synaptic membrane open -> depolarisation -> AP fired
inhibitory synapse
neurotransmitter binds -> K+/ cl- channels in postsynaptic membrane open -> hyperpolarisation of the membrane -> no AP