Neurochemical Mechanisms & Other Flashcards
Amphetamines
Facilitates release of dopamine and norepinephrine inhibitng reuptake
Benzodiazepines
Depressant
Facilitates binding process of GABA to norepinephrine
Methylphenidate
Action on dopamine reuptake inhibitor
Scopolamine
Blocking Acetylcholine Receptors
Caffeine
Blocks adenosine receptors.
Adenosine is inhibitory to primarily acetylcholine and dopamine
Affects the cortex
Increases glucose in cells
Volatile Organic Ingredients
Expand neuronal cell membranes causing disturbances in Na and K channels making a less excitable cell
Ethyl
- Inhibit glutamate
- Enhance Gaba
- Glutamate is excitatory
- Gaba is inhibitory
Salvia
Activator of Kappa opioid receptors
Barbiturates
Depressant
Reduce glutamate and increase affinity of Gaba
(Depresses RAS at low doses and depressed CNS at high doses)
Psilocybin
Agonist of several serotonin receptors
Why do females have a higher BAC than men
- Smaller size
- Less alcohol dehydrogenase
- Contraceptives slow drug metabolism
- Males have a higher water content
What causes hangovers?
- Dehydration
- Congeners
- Withdrawal
Nicotine
Stimulates nicotine subtype of acetylcholine receptors by mimicking acetylcholine