Neurobiology 1 Flashcards

1
Q

The two major control systems in the body

A

The Nervous system and the endocrine system

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2
Q

What regulatory system is slow, sustained

A

Endocrine System

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3
Q

What regulatory system is rapid, transient

A

Nervous System

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4
Q

3 overlapping functions of the nervous system

A

Sensory input-> Integration(by interneurons)-> Motor Output (effectors)

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5
Q

Where does integration of sensory inputs occur

A

Central Nervous System (Brain and Spinal Chord)

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6
Q

Where does sensory input and motor output occur

A

Sensory receptors, Peripheral Nervous system, and effectors(legs)

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7
Q

What is the nervous system composed of

A

Neurons and Glia

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8
Q

Definition of Neuron

A

Structural and functional unit responsible or transfer of information via electrical and chemical communication

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9
Q

What is the neuron’s funtion

A

To conduct electrochemical impulses

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10
Q

What are electroimpulses caused by neurons called

A

Nerve inpulses or action potentials

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11
Q

What are neurons polarized both structurally and functionally for

A

For flowing information unidirectionally through its axon

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12
Q

Components of the neural cell body

A

Nucleus, cellular organelles, Nissl bodies (rough ER)

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13
Q

What are Nissl bodies

A

Rough ER, or sites of protein synthesis

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14
Q

How do you stain Nissl bodies

A

Cresyl violet stain

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15
Q

Who developed the staining method for Nissl bodies

A

Franz Nissl

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16
Q

What is the axon

A

Cystoplasmic extension of the neuron

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17
Q

Components of axon

A

Microtubules, Smooth ER, and vesicles.

NO ROUGH ER!

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18
Q

How many axons per neuron

A

Only 1

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19
Q

How wide are axons? (Not long)

A

Only microns in diameter

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20
Q

How long can axons grow

A

As long as 1 meter

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21
Q

What is transported through the axon

A

Vesicles filled with neurotransmitters and neuropeptides

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22
Q

Where are axonal vesicles sevreted

A

The synapse cleft or extracellular space

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23
Q

When are neurotransmitters not released by the axon

A

Development or injury

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24
Q

What happens in axons during development or injury

A

Ribosomes go through active protein synthesis

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25
Where do axonal ribosomes during during development or injury come from
Neighboring glial cells by the tunneling of nanotubes between cells
26
What are mirotubules
Conveyor belts running along the entire length of the axon that also serves a cytoskeletal role
27
Microtubule functions:
To move vesicles, organelles like mitochondria. All via attachment of proteins called tubulins
28
What is the chemical synapse
Junction between two neurons. Electrical activity in one alters the electrical activity in the other
29
Ho do neurons communicate
Neurotransmitters
30
What is the neuromuscular junction
Synapse between motor neuron and a muscle neuron and a muscle fiber
31
What part of the neuron is highly branched
Dendrites
32
What varies among different types of neurons
The number of dendrites. Even among the same dendrite over a period of time
33
Dendrite function
To receive information from other neurons and carry the information toward the neuron's cell body as an electrical signal
34
What are dendritic spines
Projections that grow off of a dendrite
35
Function of dendritic spines
Site of signal reception - where synapses are located. Have receptors for neurotransmitters
36
What is neuroplasticity
When dendritic spines can change on a minute-to-minute basis
37
What is the presynaptic neuron responsible for
Carries electrical signals to the synapse and releases neurotransmitters into the synaptic cleft
38
What is the postsynaptic neuron responsible for
Carries electrical signals away from the synapse via the dendrites
39
What is the postsynaptic density
Receptors (for neurotransmitters) that are located in the postsynaptic terminal
40
Where is the axon hillock
The region where the axon joins and emerges from the cell body
41
What is the axon hillock responsible for
Plays an essential role in integration and transmission of nerve signals
42
Where is the transmembrane protein barrier located
Between the neuron's cell body and the axon hillock
43
What is the transmembrane protein barrier
The region that separates the plasma membrane of a neuron's cell body and the axon hillock. Made of actin filaments.
44
Axon hillock interactions
No synapses form from the axon hillock nor do any interact with it
45
What is the axon hillock responsible for
To evaluate the nature of a signal received by the dendrites and the cell body. Integrates electrical signal and determines response.
46
Where is the action potential generated
The axon hillock is where the action potential is generated
47
What are afferent neurons (sensory or receptor neurons)
Neurons that carry nerve impulses from receptors or sensory organs towards the Central Nervous System
48
What are interneurons
Neurons that relay information from afferent neurons to efferent neurons. Interneurons are only found in the Central Nervous System
49
What are efferent neurons (motor neurons)
Carry nerve impulses away from the Central Nervous System to effectors such as muscles
50
What are oligodendrocytes
Glial cells in the Central Nervous System that form myelin to insulate axons
51
What are astrocytes
Glial cells in the Central Nervous System that provide structural and metabolic support for neurons with material secured form the blood
52
What type of glial cells for the blood-brain barrier
Astrocytes form the blood-brain barrier
53
What are microglia
Glial cells in the Central Nervous System that are meant for neuronal maintenance by removing cell debris
54
When are microglia activated
During trauma or disease
55
What are microglia similar to
Macrophages that remove cell debris
56
What are ependymal cells
Glial cells in the Central Nervous System that line the brain ventricles
57
What are ependymal cells responsible for
To exchange molecules between ventricles and the brain
58
What is a supporting cell of the Peripheral Nervous System (PNS)
Shwann cells
59
What are Scwann cells responsible for
They form a myelin sheath to insulate axons in the Peripheral Nervous System (PNS)
60
Ratio of neurons and glial cells in the human brain
1 to 1. Differs in species