Neuroanatomy (Melissa) Flashcards

1
Q

Structure and function of the brain stem?

A

Structure:
Midbrain
Pons
Medulla

Function:
Conduit for ascending & descending tracts connecting spinal cord to cerebrum and cerebellum

Contains important reflex centres associated with control of respiration, heart rate & blood pressure, and consciousness

Contains cranial nerve nuclei:
- Cranial nerves III - XII emerge from it.

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2
Q

Spinal nerves overview

A

Each spinal nerve has Roots that join together to form mixed* spinal nerves which then branch to reach their target structures in the body

Each segment of the spinal cord gives rise to a pair of spinal nerves that consist of:
1. Axons of motor neurons that innervate a group of muscles
2. Axons of sensory neurons that innervate a defined area of skin
3. Axons of sympathetic neurons to structures in the body wall that control body temp (blood vessels, sweat glands etc.)

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3
Q

What are cranial nerves?

A

Cranial nerves are the peripheral nerves in the head and neck, and they emerge from the brainstem (except I and II)

They follow a different pattern to spinal nerves

They can be purely sensory, purely motor, or mixed

They dont have the architecture of the spinal nerve

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4
Q

Cranial nerve locations

A

From front of brain to back of brain it goes
- Nerve I –> nerve XII

Cranial nerves arise:
- From the brain (I and II)
- From the brainstem (III through XII)

Midbrain = III and IV
Pons = V, VI, VII, VIII
Medulla = IX, X, XI, XII

They exit through the foramina (holes) in the skull

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5
Q

Cranial nerve names

A

I = Olfactory
II = Optic
III = Oculomotor
IV = Trochlear
V = Trigeminal
VI = Abducens
VII = Facial
VIII = Vestibulocochlear
IX = Glossopharyngeal
X = Vagus
XI = (Spinal) Accessory
XII = Hypoglossal

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6
Q

Which cranial nerves only contain sensory neurones and fibres?

A

I - Olfactory
- Sense of smell
- Neurones located in nasal epithelium

II - Optic
- Sense of sight
- Neurones located in retina

VIII - Vestibulocochlear
- Hearing and balance
- Neurones located in spiral ganglion and vestibular ganglion

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7
Q

Which cranial nerves only contain motor neurones and fibres?

A

III - Oculomotor
- Eye movements
- Neurones located in midbrain

IV - Trochlear
- Eye movements
- Neurones located in midbrain

VI - Abducens
- Eye movements
- Neurones located in the pons

XI - Accessory
- Motor to specific neck muscles
- Neurones located in spinal cord

XII - Hypoglossal
- Motor to tongue
- Neurones located in medulla

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8
Q

Which cranial nerves have a mix of motor and sensory neurones and fibres?

A

V - Trigeminal
- General (Head, Neck, Face, Motor, Muscles)
- Sensory neurones located throughout brainstem
- Motor neurones located in pons

VII - Facial
- Special Sensory - (Taste (gustation), Motor, Muscles (facial expression))
- Sensory neurones located throughout brainstem
- Motor neurones located in pons

IX - Glossopharyngeal
- Special sensory (gustation)
- General sensory (Tongue and Pharynx)
- Motor (Part of pharynx)
- Sensory neurones located throughout brainstem
- Motor neurones located in pons

X - Vagus
- Special Sensory (gustation)
- Motor (Part of larynx, pharynx)
- Sensory neurones located throughout brainstem
- Motor neurones located in medulla

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9
Q

Which cranial nerves also carry parasympathetic fibres?

A

III - Oculomotor
- Carries parasympathetic fibres to the eye

VII - Facial
- Carries parasympathetic fibres to nasal and salivary glands

IX - Glossopharyngeal
- Carries parasympathetic fibres to salivary glands

X - Vaus
- Carries parasympathetic fibres to heart, lungs and GI tract

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10
Q

What is the limbic system and what is its structure?

A

Relates to brain structures that deal with emotion, memory, and basic drives. Species preservation, self preservation.

Interconnected structures in telecephalon & diencephalon.

Sits on/around top of the brainstem.
Major component parts:
- Hypothalamus (output)
- Amygdala (input)
- Hippocampus (input)

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11
Q

What is the hypothalamus?

A

It is part of the diencephalon

Regulates homeostasis (autonomic control)

Helps control hunger, thirst, body temperature, hormones

Regulates sexual motivation & other emotional behaviours

Interacts with the endocrine system:
- Communicates with pituitary gland for hormone production/release

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12
Q

Hypothalamus role in the limbic system

A

It is the primary output node of the limbic system, with connections to the frontal lobes and brainstem

Receives input from hippocampus and amygdala

Suprachiasmatic nucleus - circadian rhythms

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13
Q

What is the amygdala?

A

Located within temporal lobe and is comprised of a group of nuclei

It is the emotional centre of the brain; Fear centre of the brain

Controls aggression (‘fight’) and (‘fear’)

Responsible for arousal, fear, excitement, anxiety, violence

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14
Q

Amygdala role in the limbic system

A

Has reciprocal connections with many brain regions (hippocampus, brain stem, diencephalon, olfactory cortex, etc).

Various (sensory) stimuli and autonomic input converge in amygdala

Generates ‘learned’ emotional responses

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15
Q

What is the hippocampus?

A

Located within temporal lobe

Involved in spatial memory

Memory processing (storage - short & long; consolidation, encoding, retrieving)

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16
Q

Hippocampus anatomy

A

Hippocampus (CA1 - CA4)

Dentate gyrus encompasses CA4 mainly

Parahippocampal gyrus
Subiculum (Main output)
Entorhinal cortex (Input)

17
Q

What is the trisynaptic circuit?

A

It is 3 interconnected afferent pathways, taking information into the hippocampus for processing (memory retrieval)

Consists of 3 cell groups:
- Granule cells in dentate gyrus
- Pyramidal cells in CA3
- Pyramidal cells in CA1

18
Q

Pathway of each synapse in the trisynaptic circuit in memory retrieval?

A

(synapse 1)
- Entorinal Cortex -> dentate gyrus via the perforant pathway

(synapse 2)
- Dentate gryus -> CA3 via mossy fibres

(synapse 3)
- CA3 -> CA1 via Schaffer collaterals

Major output occurs via subiculum

Final output of the hippocampus is via the fornix

19
Q
A