Neuroanatomy Flashcards
Grey matter composed of
neurons
White matter composed of
myelinated axons, glial cells
Where does CNS interface with PNS?
at the dorsal and ventral horns
What are nissl granules
granules of RER with free ribosomes scattered throughout most of the cytoplasm. Site of protein synthesis.
Neurolemma
Sheath of Schwann that surrounds the axon of the neuron in PNS
3 types of glia cells
Astrocytes, oligodendroglia, microglia
Main functions of astrocytes
BBB formation, regulation, and maintenance, neuronal metabolism of CNS, NT reuptake, have pseudopodia-like extensions that surround outer capillary wall
BBB allows…
oxygen, carbon dioxide, amino acids, a few sugars, lipid-solube substances
most common CNS tumor in U.S.
astrocytoma
Principle proteins involved in myellinization in CNS by oligodendroglia cells
Myelin basic protein and proteolipid protein
Examples of demyelinating disorders of CNS
MS and Shy-Drager
Microglia origin
Derived from monocytes and macrophages
Problems with microglia cells may result in..
alzheimer’s dementia and other dementias
Location of ependymal cells
Line the central canal of spinal cord and ventricles of brain
Function of microglia cells
Ramified (dormant) until activated by injury. Then phagocytize cells and release cytokines.
Cranial nerves in pons
V, VI, and VII, and part of VIII
cranial nerves in medulla oblongata
CN VIII- XII
What does medulla oblongata contain?
Respiratory and cardiac centers
How many spinal nerves
31
spinal cord extends from
Foramen magnum to L2-L3
White matter grouped into..
Dorsal, ventral and lateral columns
Meninges composed of 3 layers
Dura, arachnoid, and pia mater
What is filled with CSF
subarachnoid space
Pia mater extending from base of the spinal cord and attaches terminally to stabilize cord
Filum terminale
What separates cerebellum from inferior portion of occipital lobes?
tentorium cerebelli
Infection of meninges
Meningitis
Infection of arachnoid and pia mater
Leptomeningitis
PE finding in Meningitis
Brudzinski’s sign-flexion of the hips with raising of the head