Neuro Med Review Sheet

Question 1

Ceftriaxone

Answer 1

Rocephin

Cat: Cephalosporin

Use: Meningitis

Dose: 2g IV q12h x7-14 days

AE: D, neutropenia, thrombocytopenia, platelet dysfunction

CI: hypersensitivity, hyperbilirubinemic neonates

Question 2

Rifampin

Answer 2

Rifadin

Cat: anti-tubercular

Use: Meningitis ppx

Dose: 600mg PO q24h x 4days for H. flu
OR 600 mg PO q12h x 4 doses (Neisseria)

AE: rash, anorexia, cramps, N/V/D, pseudomembranous colitis, elevated LFTs

CI: hypersensitivity, concurrent use of amprenavir or other protease inhibitors

Question 3

Vancomycin

Answer 3

Vancomycin HCl

Cat: Glycopeptide

Use: Meningitis (>1 month)

Dose: 30-60mg/kg/day in divided doses q8-12hrs

AE: nephrotoxicity, otoxicity, Red neck/man syndrome

CI: hypersensitivity

Question 4

Lorazepam

Answer 4

Ativan

Benzodiazepine

AED

For status: 4mg slow IV (max rate 2mg/min), MR in 5-10min

AE: sedation, ataxia, confusion

CI: hypersensitivity, acute narrow angle glaucoma, sleep apnea, severe respiratory depression

Question 5

Topiramate

Answer 5

Topamax

Anti-convulsant (misc.)

Use: AED

AE: slowed thinking, speech difficulties, decreased appetite, decreased cognitition, HA, diplopia. Pg D

CI: (ER) alcohol use, metabolic acidosis with concominant metformin

Question 6

Valproic Acid

Answer 6

Depakote

Anticonvulsive/antimanic agent

AED

15mg/kg/day –> inc by 5-10mg/kg/day weekly until therapeutic levels are reached. Max: 60mg/kg/day

AE: Tremor, weight gain, hepatic failure, thrombocytopenia, N/V, ataxia, sedation. Pg D

CI: hypersensitivity, hepatic disease, urea cycle disorders, pregnant women for the prevention of migraine

Question 7

Donepezil

Answer 7

Aricept

Acetylcholinesterase inhibitor

AD Dementia

5mg qd; may increase to 10mg qd after 4-6 weeks

AE: N/V/D, anorexia, weight loss, bradycardia

CI: hypersensitivity

Question 8

Carbidopa and Levodopa

Answer 8

Sinemet

Dopamine precursor

Parkinson’s Disease

AE: N/V, HoTN

CI: hypersensitivity, narrow-angle glaucoma, MAOI use (can use with MOAB), hx of melanoma

Question 9

Interferon Beta-1a

Answer 9

Rebif

Interferon

MS

AE: depression, HA, flu-like sx, ISR

CI: hypersensitivity, pregnancy lactation

Question 10

Sumatriptan

Answer 10

Imitrex

5-HT Receptor Agonist

Abortive Migraine Therapy (mild-severe)

25mg (max 100mg) po x1; MR after 2hr (max 200mg/24hr)

AE: dizziness, sensation of warmth, chest fullness, N = MC; Rarely – angina, arrhythmia, cerebral & myocardial ischemia. Pg C

CI: hypersensitive, ischemic heart disease, cerebrovascular syndromes, peripheral vascular disease, uncontrolled HTN

Question 11

Amitriptyline

Answer 11

Elavil

TCA

Migraine ppx, chronic pain mgmt.

30-150mg qhs

AE: drowsiness, wt gain, anticholinergic effects

CI: urinary retention, heart block

Question 12

Travaprost

Answer 12

Travatan Z

Anti-glaucoma

Glaucoma

AE: inc iris pigmentation, growth of eyelashes, itching (LC – dryness, visual disturbance, burning, eye pain, inc pigmentation of skin at eye)

CI: hypersensitivity

Question 13

Timolol

Answer 13

Timoptic

Ophthalmic Nonselective Beta Blocker

Glaucoma

AE: minimal – stinging on application, dry eyes, corneal anesthesia, blepharitis, blurred vision. Systemic: dec HR and BP, bronchospasm, masked hypoglycemia sxs, CNS sedation.

CI: asthma, bradycardia, unstable HF, sometimes COPD