NEURO (ETIOLOGY, BRAIN FUNCTION) Flashcards
relays motor and sensory information from various locations to the cerebral cortex
thalamus
reverse disruption between ras and thalamus (disorder)
delirium
● regulate emotional experiences and expressions; ability to control our impulses
● involved with the basic drives of sex
limbic system
disorder associated with limbic system
-anxiety
-borderline pd
regulate hpa axis
hippocampus
Shrinkage of hippocampus
alzheimer’s disease
What happens to hippocampus during extreme stress
shrinks
Why there is a damage in the hippocampus of those with PTSD
Because HPA axis is not regulated properly
it is involved in processing emotions, pain, and behavior regulation ; also helps to regulate autonomic motor
function
cingulate gyrus
increased activity in cingulate gyrus
OCD
fear and anxiety ; processing fearful and threatening stimuli; emotional responses
amygdala
larger and no/less activation in amygdala
Children with ASD
Disorders associated with amygdala
Anxiety disorders
Depression
Deficits in amygdala
Antisocial personality disorder
Increased activation in amygdala
borderline pd = emotion dysregulation
dopaminergic area of the brain
caudate nucleus
smaller caudate nucleus
ADHD
● outer surface of cerebrum; largest part of the forebrain
● distinct human qualities, look to the future, plan, reason, create
Cerebral cortex
where ventricles are located
Cerebral cortex
enlarged ventricles
Schizophrenia
Schizotypal PD
Shrinkage in the cerebral cortex
Alzheimer’s disease
Increased activity in cerebral cortex
OCD
largest part of the brain
Cerebrum
Damage in left hemisphere
Schizotypal
● verbal and other cognitive abilities
● left temporal, parietal, and occipital regions: phonological awareness
Left hemisphere
perceiving the world around us and creating images
Right hemisphere
integrate sensory info; move our bodies through space and manipulate objs in our world
Parietal lobe
Less temporal lobe gray matter
Schizotypal PD
increased activity in frontal
OCD
less gray matter in the pfc
Psychopaths
smaller and deficits in the frontal lobe
ADHD
Less activity in the medial prefrontal cortex
Anxiety disorders
- Disruption of the orbital
frontal cortex’s role in inhibiting amygdala activation combined w/ changes in serotonin system
IED
Low activity levels and structural changes in the pfc (esp in the anterior cingulate cortex)
Borderline PD
● lower and more ancient part of the brain
● breathing, heart rate, body temp, sleep wake cycle ; automatic functions
Brainstem
abnormalities in cerebellum ; connection with motor coordination is not clear
Cerebellum
The Little brain
Cerebellum
deterioration of basal ganglia
huntington’s disease
parkinson’s
Those with _________ had greater activation in ventral striatum when viewing images of underweight individuals
Anorexia nervosa
Heightened HPA
Trauma disorders
Mechanism that mediates the effect of stressors by regulating numerous physiological processes, such as metabolism, immune responses, and the autonomic nervous system
HPA Axis
dysregulation/ overactivity of hpa axis is linked to
Depression
Some research suggests that diminished function of the __________ system could help explain the deficits in pleasure, motivation, and energy in major depressive disorder
Dopamine
dopamine receptors may be overly sensitive in what disorder
Bipolar disorder
What neurotransmitter is both low in depression and mania
Serotonin
Among all of the mood disorders which is the most heritable?
Bipolar disorder
In what disorder is the amygdala elevated even without medication?
MDD
T or F?
Amygdala hyperreactivity to emotional stimuli in depression is just the aftermath of being depressed
FALSE
amygdala hyperreactivity to emotional stimuli in depression might be part of the vulnerability to depression rather than just the aftermath of being
depressed