NEURO DZ Flashcards
All congenital disorders are hereditary
f. are not
- Peripheral nerve and muscle disorders are common in horse
f. rare
cause of narcolepsy
unknown
breeds predisposed to narcolepsy
Lipizzaners, Miniature horses, Shetland ponies, and Suffolks
narcolepsy is a ___ disorder
cerebral
term for muscle weakness
cataplexy
narcolepsy is a ___ sleep disorder
rem
___ and __ are drugs admin to narcolepsy with monitoring levels of ___
atropine and physostigmine
hypocretin
- responsible for wakefulness and sleep activity
hypocretin/orexin
antidepressant drug possible tx for narcolepsy
imipramine
Hyperkalemic periodic paralysis (HYPP) is a peripheral nerve dominant muscle disorder
autosomal dominant
breeds predisposed to HYPP
- Quarter horses, american paint, appaloosa, quarter horses crossbreeds
what is fasciculation
muscle twitching
age for HYPP
2-3 yrs
resp distress in HYPP is due to paralysis of
upper resp muscles
a peripheral nerve and
muscle disorder
HYPP
what diet predisposes HYPP
K-rich
definitve dx for HYPP
dna testing
sx to - relieve airways due to muscle paralysis
tracheostomy
in mild HYPP, __ is stimulated for transfer excess K in blood to muscles - increase uptake of potassium
insulin
tx for stringhalt
surgical resection of the lateral digital extensor
phenytoin
* acepromazine
- Equine reflex hypertonia
stringhalt
drugs for for recurrent episodes: of HYPP
- acetazolamide
- hydrochlorothiazide
degenerative diseases of the peripheral nervs
stringhalt, equine laryngeal paralysis
peripheral nerve diseases caused by toxins
botulism,shakerfoalsyndrome,ionophore toxicity
2 categories of stringhalt
acquired
idiopathic
predisposition of Equine laryngeal paralysis
male and large breeds
how to dx stringhalt
clinical signs
* diagnostic imaging * gait analysis
plant assoc stringhalt is due to ingestion of?
false dandelion: Hypochaeris radicata, also known as cat’s ears
- “Aka: Australian stringhalt”
sporadic stringhalt
agent of shaker foal syndrome
c. botulinum
source of shaker foal syndrome
- rotting carcass and vegetation:
def dx for shaker foal
toxicology
- stilted gait
- muscle tremors
- inability to stand
- difficulty in swallowing
- But Can chew
- constipation
shaker foal
Animals that die of botulism is usually caused by:
Cardiac or respo rate problems due to paralysis of the muscle
3 forms of organophosphate poisoning
- Acute
- Intermediate
- Delayed
acute organophosphate poisoning inhibits this enzyme leading to ___ signs
acetylcholinesterase
- Cholinergic: GI motility
- Diarhrea, urination, myosis, bradycardia, bronchospasm, excitation of skeletal muscles, lacrimation, salivation, sweating
form of organophos poisoning
degeneration of nerves
delayed
form of organophos poisoning generalized muscle weakness - dilated pupils
intermediate