Neuro drugs - passmedicine

Question 1

What are the indications for carbamazepine?

Answer 1

first line for partial seizure prophylaxis
neuropathic pain - trigeminal neualgia, diabetic neuropathy
bipolar disorder

Question 2

What is the mechanism of action of carbamazepine?

Answer 2

binds to sodium channels to increase refractory period

Question 3

What are the main adverse effects of carbamazepine?

Answer 3

P450 enzyme inducer
dizziness and ataxia
drowsiness
headache
visual disturbances- diplopia 
steven-johnson syndrome 
leucopneia and agranulocytosis 
syndrome of inappropriate adh secretion