Neuro-Drugs Flashcards
1
Q
Which family of drugs contain acebutolol
A
Beta 1 blocker
2
Q
Does edrophonium cross into the CNS
A
No
3
Q
What is the location of target receptor for estrogens
A
Nuclear estrogen receptors
4
Q
What is homatropine used to treat
A
Ophthalmology
5
Q
What is Trihexyphenidyl used to treat
A
Movement disorders such as tremors and rigidity in Parkinson’s (M1 antagonist)
6
Q
Which family of drugs contain tiotropium
A
Antimuscarinic
7
Q
What is procyclidine used to treat
A
Movement disorders
8
Q
Which family of drugs contain cyclopentolate
A
Antimuscarinic
9
Q
Which family of drugs contain Acetylcholine
A
Direct acting Cholinomimetics
10
Q
Which family of drugs contain dicyclomine
A
Antimuscarinic
11
Q
Which family of GPCR ligands contains histamine
A
Biogenic amines
12
Q
Which family of GPCR ligands contains prostacyclin
A
Lipids
13
Q
Which family of drugs contain hyoscyamine
A
Antimuscarinic
14
Q
What are the side affects of alpha blockers
A
Orthostatic hypotension
Reflex induced tachycardia
15
Q
Which family of drugs contain dobutamine
A
Beta agonists
16
Q
What is the target for spiralactone
A
Antagonist for aldosterone receptor
17
Q
Which family of drugs contain ephedrine
A
Increased release and direct adrenergic receptor agonists
18
Q
Which family of drugs contain nadolol
A
Beta 1 and 2 blockers
19
Q
What is the target for succinylcholine
A
Antagonist at NMJ
20
Q
Which family of GPCR ligands contains opioids
A
Peptides/proteins
21
Q
What is the result of using etoposide
A
Causes DNA, activation of p53 and apoptosis
22
Q
What type of receptor is used to transmit Leptin
A
JAKSTAT
23
Q
What is the target for digoxin
A
Sodium/potassium pump
24
Q
Which drug is used for cardiogenic shock
A
Dopamine
Dobutamine
25
What is solifenacin used to treat
Urinary disorders (selective M3 antagonist)
26
Which family of GPCR ligands contains ADP
Nucleotides
27
Which family of drugs contain procyclidine
Antimuscarinic
28
What conditions is bethanechol used to treat
Non obstructive GI issues
| Non obstructive urinary issues
29
Which antimuscarinic drug is used for a longer time of action
Tiotropium (M3 antagonist)
30
Which family of drugs contain Trihexyphenidyl
Antimuscarinic
31
What type of receptor is used to transmit erythropoietin
JAKSTAT
32
Which family of drugs contain Physostigmine
Cholinesterase inhibitors
33
What is neostigmine used to treat
Myasthenia gravis
Reverse nondepolarizing NMJ agents (curare)
Urinary retention
34
What is the location of target receptor for progesterone
Nuclear progesterone receptors
35
Which family of drugs contain fesoterodine
Antimuscarinic
36
What is methacholine used for
An asthma challenge for pulmonary testing
37
Which family of drugs contain tolterodine
Antimuscarinic
38
Which family of drugs contain selegiline
Inhibators of MAO
39
What is the location of target receptor for glucocorticoid
Nuclear glucocorticoid receptors
40
What is ritodrine used to treat
Premature labor
41
Which family of drugs contain Atropine
Antimuscarinic
42
Which family of drugs contain isoproterenol
Beta agonist
43
Which family of drugs contain Scopolamine
Antimuscarinic
44
Which family of drugs contain methacholine
Direct acting cholinomimetics
45
Which family of drugs contain fenoldopam
Dopamine agonists
46
What is phyridostimgine used to treat
Long term treatment for myasthenia gravis
47
What is carbachol used to treat
Acute angle glaucoma
48
Which family of GPCR ligands contains norepinephrine
Biogenic amines
49
What is tropicamide used to treat
Ophthalmology
50
Which family of drugs contain penylephrine
Alpha antagonist (alpha 1)
51
Which family of drugs contain tropicamide
Antimuscarinic
52
Which family of drugs contain oxybutynin
Antimuscarinic
53
Which family of GPCR ligands contains Thromboxane A2
Lipids
54
What is the overall result of bethanechol
Increased secretion of gut and urinary tract
55
What type of receptor is used to transmit NGF
Tyrosine kinase
56
Which family of drugs contain darifenacin
Antimuscarinic
57
What is Dicyclomine used to treat
Gastrointestinal disorders
58
What type of receptor is used to transmit PDGF
Tyrosine kinase
59
Which family of drugs contain pilocarpine
Direct acting cholinomimetics
60
What class of drug is given for prevention of premature labor
Beta 2 agonist
61
What is varenicline used to treat
Cessation of smoking
62
Which family of drugs contain Pyridostigmine
Cholinesterase Inhibators
63
Which family of drugs contain norepinephrine
Alpha and Beta agonists
64
What type of receptor is used to transmit IGF-1
Tyrosine Kinase
65
Which family of GPCR ligands contains Epinephrine
Biogenic amines
66
Which class of drug is given for glaucoma
Alpha 2 agonist
67
What type of receptor is used to transmit EGF
Tyrosine kinase
68
What is phenylephrine used to treat
-nasal congestion
-ophthalmology
-
69
Which family of drugs contain Echothiophate
Cholinesterase Inhibitors
70
What is dobutamine used to treat
Beta 1 > beta 2
| Increased heart rate, contractility, CO
71
What are the treatments for bronchial asthma
Beta-2 agonists
Albuterol
Terbutaline
72
What is tolterodine used to treat
Adult urinary incontinence (M2 antagonist)
73
Which family of drugs contain atenolol
Beta 1 blockers
74
What type of receptor is used to transmit interleukin 2-10,15
JAKSTAT
75
Which family of drugs contain betaxolol
Beta 1 blockers
76
Which family of drugs contain Pralidoxime
Cholinesterase regenerator
77
What is the mechanism of action of Prazosin
Alpha 1 Adrenergic receptor antagonist
78
Which drug should not be given for a depolarizing NMJ blocking agent
Acetylcholine esterase inhibitor
79
What type of drug class is propranolol
Beta blocker
80
What is the property of binding and target for phenoxybenzamine
Irreversible binding to alpha receptors
81
Which family of drugs contain phentolamine
Nonselective alpha 1 and 2 antagonist
82
Which family of GPCR ligands contains Acetylcholine
Biogenic amines
83
Which family of drugs contain Galantamine
Cholinesterase Inhibators
84
Which family of GPCR ligands contains Glutamate
Aminoacids
85
What is biperiden used to treat
Movement disorders
86
What type of receptor is used to transmit VEGF
Tyrosine kinase
87
What is orphenadrine used to treat
Movement disorders
88
What is the result of result of carbachol
Pupillary constriction
89
What is hyoscyamine used to treat
Gastrointestinal disorders
90
Which family of drugs contain pindolol
Beta 1 and 2 blockers
91
Which drug is used in long term treatment for hypertension
Alpha 2 agonist
92
What is the effect of phenylephrine administration
Slowed heart rate (baroreflex response)
Increased blood pressure
Mydriasis
Decreased nasal secretion
93
What is the effect on the level of ENaC and Na/K ATPase with the administration of spironolactone
Decreased expression of ENaC and sodium/potassium pump
94
What is the result of Prazosin
Anti hypertension drug
95
Which family of drugs contain cocaine
Inhibition of NE and DA reuptake
96
Which drug is used for chronic hypotension
Ephedrine
97
Which family of drugs contain homatropine
Antimuscarinic
98
What is the property of binding and target for phentolamine
Reversible binding to alpha receptors
99
What are the overall effects of pilocarpine
Increased salivation
Accommodation of lens
Increase aqueous humor outflow
Meiosis
100
What is terbutaline used to treat
Prevents premature labor
101
Which family of drugs contain bethanechol
Direct acting cholinomimetic
102
Which drug is used in hypertension emergencies
Fenoldopam (dopamine)
103
Which family of GPCR ligands contains Angiotensin
Peptides/protein
104
Which family of drugs contain penbutolol
Beta 1 and 2 blockers
105
What is atropine used to treat
```
Heart block (increased AV node conduction) (M2 antagonist)
Cholinergic poisoning (organophosphates and AChE inhibators) (M1 anatgonist)
Opthamalogy (M1)
```
106
Which family of drugs contain carbachol
Direct acting cholinomimetics
107
Patients on Varenicline need to be watched for which symptom
Depression and suicidal thoughts
108
What can edrophonium be used to test for
Given to see if its AChE inhibator poisoning or myasthenia gravis
109
What is the use of dobutamine
Short term use in acute heart failure
110
Which family of drugs contain Donapezil
Cholinesterase Inhibators
111
What drug is used in induction of mydriasis for eye examination
Phenylephrine (alpha 1 agonist)
112
Which family of GPCR ligands contains serotonin
Biogenic amines
113
Which eye related disorder is contraindicated with muscarinic antagonists
Glaucoma
114
What is physostigmine used to treat
Atropine overdose
115
What type of receptor is used to transmit growth hormone (somatostatin)
JAKSTAT
116
Which family of drugs contain methylphenidate
Increased DA and NE release, decreased reuptake
117
Which family of drugs contain Neostigmine
Cholinesterase Inhibitors
118
What is tiotropium used to treat
Respiratory disorders such as asthma and COPD (M3 antagonist)
119
Which family of drugs contain Endrophonium
Cholinesterase Inhibitors
120
What is the target of verapamil
L type calcium channel
121
Which family of GPCR ligands contains leukotrienes
Lipids
122
What is isoproterenol used to treat
Asthma and respiratory distress
123
Which family of drugs contain varenicline
Direct acting cholinomimetics
124
Which family of drugs contain albuterol
Beta agonist
125
Which family of drugs contain guanethidine
NE release inhibator
126
What is the drug given fro stress urinary incontinence
Ephedrine
127
What is the result of using spironolactone
Increase loss of salt and water, leading to decrease in blood volume and BP
128
What is glycopyrrolate used to treat
Gastrointestinal disorders
129
Which family of drugs contain biperiden
Antimuscarinic
130
What is the location of target receptor for mineralcorticoid receptors
Nuclear mineralcorticoid receptors
131
What is the result of verapamil
- Decreased arythmias
- decreased oxygen use and chest pain
- Decreased hypertension
- Constipation
132
Which family of drugs contain phenoxybenzamine
Non selective receptor antagonist
133
What is phentolamine used to treat
Cocaine toxicity
HTN crisis
Pheochromocytoma
134
Which family of drugs contain Ambenonium
Cholinesterase Inhibators
135
What is Donepezil used to treat
Treatment of Alzheimer’s
136
What is ipratropium used to treat
Respiratory disorders such as asthma and COPD (M3 antagonist)
137
What is the use of dopamine
Congestive severe heart failure with reduced renal perfusion
138
Which family of drugs contain Propranolol
Beta 1 and 2 bloackers
139
Which family of drugs contain amphetamines
INcreased release of DA and NE, Decreased reuptake
140
What type of receptor is used to transmit Interferons
JAKSTAT
141
Which family of drugs contain lacetalol
Mixed beta and alpha 1 blocker
142
What is rivastigmine used to treat
Alzheimer’s disease
143
What is Benztropine used to treat
Movement disorders such as tremors and rigidity in Parkison’s (M1 antagonist)
144
What is the location of the receptor for thyroid hormones
Nuclear receptors
145
What is scopolamine used to treat
```
Motion sickness (M1 antagonist)
Ophthalmology
```
146
What is the target for dobutamine
Agonist for Beta 1 adrenergic receptors
147
What is the location of target receptor for Androgens
Nuclear androgen receptors
148
What is given for poisoning of organophosphates or other cholinesterase inhibitors
- Atropine (crosses into CNS and affects mAChR)
| - Pralidoxime (affects n and mAChR to get rid of flaccid paralysis)
149
Which drug is used for Hypotensive emergencies
- Norepinephrine
| - phenylephrine
150
Which family of drugs contain metyrosine
Tyorisine hydroxylase inhibator
151
What is cevimeline used to treat
Dry mouth associated with Sjegren’s
152
Which family of drugs contain Rivastigmine
Cholinesterase Inhibitors
153
What is the result of acetylcholinesterate inhibitor toxicity
DUMBBELS
| -Flaccid paralysis
154
Which family of GPCR ligands contains aminoacids
GABA
155
What is pilocarpine used to treat
Acute angle glaucoma
| Dry mouth associated with Sjogren’s
156
What is Oxybutynin used to treat
Urinary incontanence post surgery (Selective M3 antagonist)
157
Which family of drugs contain trospium
Antimuscarinic
158
Which family of GPCR ligands contains Adrenocorticotropin (ACTH)
Proteins/peptides
159
Which family of drugs contain Mecamylamine
Ganglion blockers
160
What is Galantamine used to treat
Alzheimer’s disease
161
Which family of drugs contain Tacrine
Cholinesterase inhibitors
162
What is trospium used to treat
Bladder incontinence (non selective antagonist)
163
Which family of GPCR ligands contains dopamine
Biogenic amines
164
Which family of drugs contain solifenacin
Antimuscarinic
165
What is the target of etoposide
Inhibits topoisomerase 2
166
What is cyclopentolate used to treat
Ophthalmology
167
What type of receptor is used to transmit insulin
Tyrosine kinase
168
Which family of drugs contain terbutaline
Beta agonist
169
What is endrophonium used to treat
Transiently used to treat myasthenia gravis
170
Which family of GPCR ligands contains Adenosine
Nucleotides
171
Which family of drugs contain cevimeline
Direct acting cholinomimetic
172
Which family of drugs contain organophosphate
Cholinesterase Inhibitor
173
Which family of GPCR ligands contains ATP
Nucleotides
174
Which drugs are given for complete AV block and cardiac arrrest
Epinephrine
| Isoproterenol
175
Which family of drugs contain orphenadrine
Antimuscarinic
176
Which family of drugs contain metoprolol
Beta 1 blockers
177
What is the receptor stimulated by carachol
Muscarinic and nicotinic
178
Which family of GPCR ligands contains bradykinin
Peptides/proteins
179
Which family of drugs contain gycopyrrolate
Antimuscarinic
180
What drug is given for a nonpolarizing agent at the NMJ
Neostigmine
181
Which family of drugs contain benztropine
Antimuscarinic
182
What was tacrine used to treat
Dementia
183
Which family of drugs contain phenelzine
Inhibitors of MAO
184
Which family of drugs contain clonidine
Alpha agonist (alpha 2)
185
Which family of drugs contain Ipratropium
Antimuscarinic
186
Which family of drugs contain epinephrine
Alpha and Beta
