Neuro Drugs

Question 1

Botulinum toxin

Answer 1

chronic migraine, modulating neurotransmitter

Question 2

Erenumab

Answer 2

CGRP monoclonal antibodies , vasodilator in trieminovascular , for refractory migraine well tolerated, no interaction

Question 3

Galcanezumab

Answer 3

CGRP monoclonal antibodies , vasodilator in trieminovascular , for refractory migraine well tolerated, no interaction

Question 4

Triptans

Answer 4

5HT 1b/1d on trigeminal cervical complex, brainstem/thalamus

Question 5

acetazolamide

Answer 5

Carbonic anhydrase inhibitors -reduce CSF production

Question 6

Keppra

Answer 6

SV2A and GABA. SJS, psych. Generalised seuzire young women
renal excret

Question 7

phenytoin

Answer 7

Na channel, focal seizure. SJS, agranulocytosis, ataxia, nystagmus
CYP2C93

Question 8

valporate

Answer 8

GABA. broad spectrum. SJS, agranulocytosis, weight gain, liver dysfunction, hyper ammonemia

Question 9

carbamazepine

Answer 9

NA channel. focal seizure, SJS HLA1502, agranulocytosis, DRESS HLA 3101

Question 10

lamotrigine

Answer 10

Na channel. broad spectrum. SJS

Question 11

pyridostigmine

Answer 11

acetylcholinesterase inhibitor- Mg
SE saliva, lacrimination, diarrhoea

Question 12

Eculizumab

Answer 12

complement C5 inhibitor