Neuro Flashcards

1
Q

1 weej recurrent thunderclap headache. Seizure
CT angio: sausage on a string on circle of willis

A

Reversible cerebral vasoconstriction syndrome

NSAID< pain control, BP monitor . Verapamil/nimodipine

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2
Q

cryptococcal meningitis

A

glucose reduced. predominant lymphocyte

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3
Q

TB meningitis

A

lymphocyte + polymorphs

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4
Q

encephalitis

A

altered consciouesness/lethargy./behaviour + evidence of CNS inflammation- fever, seizure/focal neuro, CSF pleocytosis, EEG, neuroimaging

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5
Q

paraneoplastic encephalitis

A

anti Hb (SCLC), anti NMDAR (ovarian), anti VGKCC ( anti LGI1, anti caspr2)

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6
Q

AMPA receptor ab

A

limbic encephalitis

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7
Q

anti GAD

A

still person syndrome -neuroendocrine

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8
Q

anti NMDA receptor

A

limbic encephalitis with psychosis, coma, seizure– overain teratoma

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9
Q

anti Hu

A

SCLC, encephalomyelitis

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10
Q

anti Ma

A

testicular, limbic/brainstem encephalitis

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11
Q

anti GM1

A

GBS

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12
Q

aquaporin 4

A

NMOSD- neuromyelitis optica

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13
Q

ganglioside Q1B

A

miller fisher

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14
Q

lambert eaton

A

proximal weakness improve with exervise, autominic, areflexia P/Q type voltage gated Ca channel, SCLC

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15
Q

PSP

A

Tau, Supranuclear palsy, early falls, impulsive, humming bird

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16
Q

Alz

A

Tau, neurofibrillary tangle

17
Q

Cortical basal degen

A

Tau, pyramidal weakness, alian limb, cognitive impair, speech apraxia

18
Q

PD

A

alpha synuclein. Tremor/rigidit, postural instabilityakinesia

19
Q

Dementia LB

A

Alpha synuclein. visual hallucination. fluctuating congition, parkinsonism

20
Q

Multi systum atrophy

A

alpha synuclin. autonomic ++ blader/bowerl. Cross bun sign

21
Q

CJD

A

rapid dementia, myoclonus (late), psych symptoms. CSF normal. EEG - periodic lateralisedepileptiform discharge . 14-3-3- protein

22
Q

cluster headache

A

1-8 attack per day, 15 min to 3 hr.
treat O2 acute attach. Triptan, verapamil. Greater occipital nerve injection

23
Q

paroxysmal hemicrania

A

2-30 min and more frequent then cluster. more common in women. Respond to indomethacinGreater occipital nerve injection Greater occipital nerve injection

24
Q

hemicrania continua

A

lasting hours/days. respond to indomethacin

25
Q

Ach-R

A

90% in MG

26
Q

anti Musk

A

40% in Mg

27
Q

low density lipoprotein receptor (LRP4)

A

20% in MG

28
Q

anti striational

A

30% adult Mg, 80% thymoma