Neuro

Question 1

1 weej recurrent thunderclap headache. Seizure
CT angio: sausage on a string on circle of willis

Answer 1

Reversible cerebral vasoconstriction syndrome

NSAID< pain control, BP monitor . Verapamil/nimodipine

Question 2

cryptococcal meningitis

Answer 2

glucose reduced. predominant lymphocyte

Question 3

TB meningitis

Answer 3

lymphocyte + polymorphs

Question 4

encephalitis

Answer 4

altered consciouesness/lethargy./behaviour + evidence of CNS inflammation- fever, seizure/focal neuro, CSF pleocytosis, EEG, neuroimaging

Question 5

paraneoplastic encephalitis

Answer 5

anti Hb (SCLC), anti NMDAR (ovarian), anti VGKCC ( anti LGI1, anti caspr2)

Question 6

AMPA receptor ab

Answer 6

limbic encephalitis

Question 7

anti GAD

Answer 7

still person syndrome -neuroendocrine

Question 8

anti NMDA receptor

Answer 8

limbic encephalitis with psychosis, coma, seizure– overain teratoma

Question 9

anti Hu

Answer 9

SCLC, encephalomyelitis

Question 10

anti Ma

Answer 10

testicular, limbic/brainstem encephalitis

Question 11

anti GM1

Answer 11

GBS

Question 12

aquaporin 4

Answer 12

NMOSD- neuromyelitis optica

Question 13

ganglioside Q1B

Answer 13

miller fisher

Question 14

lambert eaton

Answer 14

proximal weakness improve with exervise, autominic, areflexia P/Q type voltage gated Ca channel, SCLC

Question 15

PSP

Answer 15

Tau, Supranuclear palsy, early falls, impulsive, humming bird

Question 16

Alz

Answer 16

Tau, neurofibrillary tangle

Question 17

Cortical basal degen

Answer 17

Tau, pyramidal weakness, alian limb, cognitive impair, speech apraxia

Question 18

PD

Answer 18

alpha synuclein. Tremor/rigidit, postural instabilityakinesia

Question 19

Dementia LB

Answer 19

Alpha synuclein. visual hallucination. fluctuating congition, parkinsonism

Question 20

Multi systum atrophy

Answer 20

alpha synuclin. autonomic ++ blader/bowerl. Cross bun sign

Question 21

CJD

Answer 21

rapid dementia, myoclonus (late), psych symptoms. CSF normal. EEG - periodic lateralisedepileptiform discharge . 14-3-3- protein

Question 22

cluster headache

Answer 22

1-8 attack per day, 15 min to 3 hr.
treat O2 acute attach. Triptan, verapamil. Greater occipital nerve injection

Question 23

paroxysmal hemicrania

Answer 23

2-30 min and more frequent then cluster. more common in women. Respond to indomethacinGreater occipital nerve injection Greater occipital nerve injection

Question 24

hemicrania continua

Answer 24

lasting hours/days. respond to indomethacin

Question 25

Ach-R

Answer 25

90% in MG

Question 26

anti Musk

Answer 26

40% in Mg

Question 27

low density lipoprotein receptor (LRP4)

Answer 27

20% in MG

Question 28

anti striational

Answer 28

30% adult Mg, 80% thymoma