Neuro Flashcards
What is the innveration route of Tensor veli palatini
Motor nucleus of trigeminal -> F. Ovale -> V3 (mandibular branch of trigeminal)
Which nerve carries motor fibers from motor trigeminal nucleus to tensor tympani?
V3
Which nerve supplies motor function to Anterior belly of digastric?
V3
Which nerve carries motor fibers to posterior belly of digastric?
VII
Which brainstem nuclei does motor innveration to stylohoid come from?
Motor nucleus of facial nerve
Which cranial nerve carries motor fibers to stapedius?
VII
Which autonomic ganglion supplies the lacrimal gland?
Pterygopalatine ganglion via V2
What is the innervation course of the parotid gland
Inferior salivatory nu -> CN IX ->otic ganglion-> V3 -> parotid gland
Which brainstem nuclei supplies submandibular and sublingual glands?
Superior salivatory nucleus
What kind of nucleus is the Nucleus Ambiguus
Motor
What nerves carry fibers out from nucleus ambiguus?
X and IX
Which nerve carries motor fibers to stylopharyngeus?
IX
Which nerve carries motor fibers to palatoglossus?
CN X
Which nerves carry sensation fibers to the sensory nucleus of trigeminal?
V, VII, IX and X
Which nerve carries sensation to the posterior 1/3 of the tongue?
CN IX
What information does the Nucleus of solitary tract receive?
Taste from CNVII and CN IX and CN X
Visceral sensation from CN X
Which nerve carries sensation from the eyelids?
CN V1
Which nerve carries motor fibres to cricothyroid?
Superior laryngeal nerve via vagus nerve
Which nerve carries motor fibres to the intrinsic laryngeal muscles?
Recurrent laryngeal nerve
What embryological cells is the frontal bone derrived from?
Neural crest
What embryological cells is the parietal bone derrived from?
Paraxial mesoderm
What embryological cells is the laryngeals of the neck derrived from?
Lateral plate mesoderm
What 2 processes is the 1st pharyngeal arch divided into?
Maxiullary and mandibular process
What does the first pharyngeal arch membrane become?
Tympanic membrane
What does the 1st pharyngeal cleft become?
External auditory meatus
What forms the cervical sinus?
2nd 3rd and 4th pharyngeal arches
Which cranial nerve is the 1st pharyngeal arch associated with?
CN V
Which cranial nerve is the 2nd arch associates with?
CN VII
Which CN is the 3rd pharyngeal arch associated with?
CN IX
Which pharyngeus muscle is associated with the 3rd pharyngeal arch?
Stylopharyngeus
What muscles derrive from the 4th pharyngeal arch? - which nerve is is it associated with?
Muscles of pharynx and soft palate - superior laryngeal brunch of vagus
What muscles is the recurrent laryngeal nerve associated with?
Muscles of larynx - intrinsic muscles
What happens to the pharyngeal arch arteries?
Become the great vessels of the arch
What is the cause and presentation of a branchial cyst?
Failure of 2nd pharyngeal pouches to obliterate - forming a pouch filled with fluid in the neck.
Remains stationary on swallowing.
Describe treacher collins syndrome
Hyppplasia of cheeks and mandible
Colobomas/congenital scarring of eyelids
Downward slopping palpebral fissures
Poorly developed supraorbital ribs and cheeks
Receeding chin and malformation of the ear
What defect is treacher collins sd associated with?
1st pharyngeal arch neural crest defect
What genetic defect is associated with micrognathia, glossptosis, airway obstruction, cleft palate and small maxilla?
Peirre robin sequence - neural crest genetic defect
Describe Del22q11.2 syndrome
Facial dysmorphia with maxialla and mandible
Micrognathia, small mouth, posteriorly rotated ears
Cardivasciular defects
Frequent infections
Which defect includes face and cardiovascular defects?
Del22q11.2
What does the auditory tube form from?
1st pharyngeal pouch
What does the 2nd pharyngeal pouch become?
Palatine tonsil
What does the 3rd pharyngeal pouch become?
Inferior parathyroid gland and thymus
What does the 4th pharyngeal pouch become?
Superior parathyroid gland
Which arches fuse to form the tongue?
1st arch - CN v
2nd arch - regresses
3rd arch - CN IX
4th arch - CN X
What forms the nasal septum
Ethmoid bone
Septal cartilage
Vomer
What is the significance of Little’s Area?
Anastamoses of ICA and ECA
What branches supply the superior part of the nasal cavity?
Anterior and posterior ethmoidal artery - from ICA
What branches supply the inferior nasal cavity?
Sphenopalatine artery and greater palatine artery - from ECA
How does the blood supply of the nasal cavity drain?
Pterygoid plexus -> cavernous sinus
What nerves carry general sensation fibers from the noise?
V1 and V2
What muscle does the parotid duct pierce?
Buccinator
What kind of joint is between the condylar process and the mandibular fossa in the temporal bone?
Synovial
3 ligaments that stabilise the mandible
Lateral ligament
Sphenomandibular ligament
Stylomandibular ligament
Which muscle helps to open the jaw?
Lateral pterygoid
Which muscle helps in side to side movement of the mandible?
Lateral pterygoid and medial pterygoid
Which branch of V3 carries motor fibers to the muscles of mastication?
Anterior division of V3
Which nerve is responsible for headaches in TMJ syndrome?
Auriculotemporal branch of V3
What sits in the infra-temporal fossa?
Branches of V3
Otic ganglion
Branchies of VII and IX
Maxillary artery & vein
Middle meningeal artery * vein
Medial and lateral pterygoid muscles
Which division of V3 carries nerve to mylohyoid?
Posterior division -> anterior alveolar nerve -> nerve to mylohyoid
The lingual nerve is a branch of the inferior alveolar nerve - T or F?
F, lingual nerve is a branch of the posterior division of V3.
Which CN carries autonomic fibres from the superior salivatory nucleus to the pterygopalatine and submandibular ganglions?
VII
Which nerve carries parasympathetic fibres to the submandibular and sublingual glands?
Lingual nerve from v3
Which nerve carries parasympathetic fibres from otic ganglion to the parotid gland?
Auricuclotemporal branch of V3
What nerve carries sensory fibers to the maxillary gums?
Long buccal nerve from anterior division of V3
What is the only motor fiber carried by the posterior division of V3?
Nerve to mylohyoid (and anterior digastric)
List the 16 cranial nuclei in the brain stem
EW CN III motor CN IV motor CN V motor CN VII motor CN VI motor NA motor Sup salv Inf salv Dorsal vagus Hypoglossal XII
Mesencephalic V
Chief sensory V
Spinal V
Vestibularcochlear VII
NST VII IX X
What is the origin of the foreman caecum?
Remnant of the thyroid gland
If hypoglossal nerve lesion is on left side, which side will the tongue deviate to?
Left
Which nerve carries motor fiber to levator veli palatini?
CN X
Which muscle depresses the soft palate? Which nerve carries its motor fibers?
Palatopharyngeus - CN X
What is another name for the false vocal cord?
Vestibular fold
What is the innveration of the infrahyoid muscles?
Mostly Ansa cervicalis (c2 c3)
Except thyrohyoid which is C1
What are the innervations of the suprahyoid muscles
Anterior digastric is V3
Posterior digastric is VII
Mylohyoid is V3
Stylohyoid VII
Geniohyoid is C1
What nerve carry sensory fibers to larynx?
Vagus nerve
What nerve carries sensory fibers from the inner surface of the tympanic membrane?
Glossopharyngeal IX
Which 3 muscles elevate the pharyngeal wall during swallowing? Innervations?
Palatopharyngeus = X Stylopharyngeus = IX Salpingopharyngeus = X
Which vertebrae is atlas and which is axis?
C1 is atlas, c2 is axis.
What stabilises the odontoid process of c2?
Transverse ligament of the atlas
Commonest fungal meningitis in the UK?
Cryptococcus neoformans
What kind of drug is clopidogrel?
Anti-platelet
Where does the tectospinal tract originate from?
Superior colliculus in midbrain
What does the basal ganglia consist of?
Caudate nuclus Globus pallidus Putamen Subthalamic nucleus Substantia nigra
What does the striatum consist of?
Caudate and putamen
What is the input of the striatum?
Cortex
What basal ganglia structure outputs to the thalamus?
Globus pallidus
What is the direct pathway? From cortex to cortex
Cortex -> striatum -> GP -> ventolateral nucleus of thalamus -> cortex
Decreased striatum activity leads to increase or decreased motor activity?
Decreased = hypokinesia
Globus pallidus activity is excitatory or inhibitory on the ventro-lateral thalamus?
Inhibitory
Loss of globus pallidus neurones account for symptoms of huntington’s disease - T or F?
True, GP is inhibitory to thalamus and motor activity
Loss of inhibition leads to hyperkinesia
Subthalamic influence on the globus pallidus is excitatory or inhibitory?
Excitatory - therefore as GP is inhibitory to thalamus, subthalamic activity is inhibitory to motor activity.
Loss of subthalamic nuclei activity leads to hyponkinetic disorders - T or F?
False - leads to hyperkinetic disorders due to loss of excitation on GP
Loss of which basal ganglia structure leads to abulia?
Caudate nucleus
What is the motor output destination of ventral lateral thalamus?
Supplementary motor area (SMA)
Difference between function of caudate circuit and putamen circuit
Caudate circuit involved in cognitive planning of movement, initation of activity.
Putamen involved in execution of learned patterns of movement
Order in most conscious to least conscious
1) coma
2) locked in syndrome
3) persistent vegetative state
4) brain death
5) minimally conscious state
Minimally conscious state Locked in syndrome Persistent vegetative state Coma Brain death
Order in most conscious to least conscious
1) confused
2) conscious
3) stuporous
4) obtunded
5) comatose
6) delirious
7) somnolent
1) conscious
2) confused
3) delirious
4) somnolent
5) obtunded
6) stuporous
7) comatose
Where are corticopontine fibers located in the internal capsule?
Anterior limb
The lacrimal nerve from V1 supplies parasympathetic fibres to the lacrimal gland - T or F?
True, lacrimal Nerve from V1 carry sensory fibers from conjuctiva and skin of superior eyelid AND receives parasympathetic fibers from zygomaticotemporal branch of V2 bound for lacrimal gland.
Steps to test function of superior oblique?
Adduct the eyeball first which uses MR (look inwards to nose)
Then to test SO, direct gaze downwards while adducted.
IR depresses eyeball but SO enables extreme depression of eyeball, especially in adducted state.
Function of SO on its own?
Down and out
Which nerve carries sympathetic fibers to the iris to enable constriction of pupils?
V1 via nasociliary nerve
Which nerve carries motor fibres to stapedius and tensor tympani?
VII to stapedius and V3 to tensor tympani