Neuro 4 - Blood Supply to the Central Nervous System Flashcards

1
Q

What percentage of cardiac output goes to the brain?

A

10-20%

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2
Q

What percentage of liver glucose does the brain use?

A

66%

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3
Q

State the two main sources of blood supply to the brain?

A

Vertebral arteries

Internal carotid arteries

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4
Q

State the major artery that the vertebral arteries branch off.

A

Subclavian Artery

Vertebral arteries pass through the transverse foramina of the cervical vertebrae and through the foramen magnum

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5
Q

State the name of venous sinuses that are at the top and bottom of the falx cerebri.

A

Superior sagittal sinus

Inferior sagittal sinus

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6
Q

What is the name given to the place where all the sinuses meet?

A

Confluence of sinuses

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7
Q

What connects the inferior sagittal sinus to the confluence of sinuses?

A

Straight sinus

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8
Q

What vessel does the inferior sagittal sinus join with to form the straight sinus?

A

Great cerebral vein

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9
Q

Which sinus ascends to join the confluence of sinuses?

A

Occipital sinus

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10
Q

Which two sinuses run along the temporal bone?

A

Superior petrosal sinus

inferior petrosal sinus

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11
Q

Which main sinus drains into the internal jugular vein through the jugular foramen?

A

Sigmoid sinus

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12
Q

Which sinus connects the confluence of sinuses to the sigmoid and superior petrosal sinuses?

A

Transverse sinus

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13
Q

Which sinus run on either side of the pituitary stalk?

A

Anterior and posterior intercavernous sinuses

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14
Q

Which extension of dura mater separates the cerebellum from the inferior portion of the occipital lobe?

A

Tentorium cerebelli

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15
Q

Define stroke.

A

rapidly developing focal disturbance of brain function of presumed vascular origin that lasts more than 24 hours

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16
Q

Define transiet ischaemic attack.

A

a rapidly developing focal disturbance of brain function of presumed vascular origin that resolves completely within 24 hours

17
Q

What percentage of strokes are caused by infarction and haemorrhage?

A

infarction: 85%
haemorrhage: 15%

18
Q

State two causes of occlusions.

A

Thrombus

Embolism

19
Q

What is the difference between a thrombus and an embolism?

A

Thrombus - formation of a blood clot

Embolism - plugging of small vessel by material carried from a larger vessel

20
Q

Describe the perfusion fields of the brain.

A

Anterior cerebral artery supplies the medial part of both hemispheres

middle cerebral artery extends laterally and emerges from the lateral fissure

supplies front 2/3 of the lateral part of hemisphere

21
Q

Describe the location of the leg in the motor and sensory homunculus compared to the arm?

A

leg is more medial

22
Q

Describe the features of a disturbance in the anterior cerebral artery.

A

Contralateral hemiplegia in leg more than arm
disturbance of intellect and executive function
loss of appropriate behaviour

23
Q

Describe the features of a disturbance in the middle cerebral artery.

A
Classic stroke
Contralateral hemiplegia in arm ARM more than the leg
contralateral hemisensory deficits
Hemianopia
Aphasia
24
Q

Describe the features of a disturbance in the posterior cerebral artery.

A

supplies occipital lobe

causes visual defects such as homonymous hemianopia and visual agnosia

25
Q

Which parts of the brain are involved in speech and understanding language?

A

Broca - speech

wernicks - understanding language

26
Q

What are lacunar infarcts?

A

small spaces in brain due to small vessel occlusion

caused by hypertension

27
Q

State 4 types of hemorrhagic stroke and their likely causes.

A

Extradural - rapid - trauma
Subdural - slow - trauma
Subarachnoid - ruptured aneurysms
Intracerebral - spontaneous rupture of vessels

28
Q

What is the difference between the dura on the vertebral column compared to the brain?

A

dura in vertebral column has 1 layer whereas dura in skull as 2

29
Q

What are the two layers of dura in the skull called?

A

Periosteal and meningeal

30
Q

What is the name given to the fold of dura that extends between the medial surfaces of the two hemispheres?

A

Falx cerebri

31
Q

Why are extradural haemorrhages more rapid onset than subdural haemorrhages?

A

extradural are caused by rupture of a meningeal artery which is more high pressure

subdural = meningeal vein - low pressure