Neuro Flashcards
What is a tension type headache (TTH)?
A tension-type headache (TTH) is the most common type of headache and is often described as a dull, aching pain or pressure around the forehead, temples, or back of the head
H&E of TTH
- Bifrontal/occipital pain
- Episodic in nature
- Pressure/band-like tightness around head
- Lasts a few hours
RF of TTH
- Stress
- Fatigue
- Mental tension
Investigations of TTH
First investigation is clinical diagnosis (normal neuro exam) and diagnosis via exclusion
Consider (if headache is refractory or progressing):
- CT sinus : exclude sphenoid sinusitis
- MRI : exclude brain tumour
- Lumbar puncture : exclude infective causes, sinus venous thrombosis or pseudotumour cerebri
Management of TTH
Acute - simple analgesics (aspirin, paracetamol, ibuprofen or naproxen)
Chronic (> 7-9/month)
- antidepressant (amitriptyline or doxepin)
- muscle relaxant (tizanidine)
- consider non-drug therapies
Prophylactic acupuncture
What is a Stroke?
- AKA Cerebrovascular Accident
- Represents a sudden interruption in the vascular supply of the brain
- Two types are haemorrhagic and ischaemic
H&E for Stroke
- motor weakness
- dysphagia
- swallowing problems
- homonymous hemianopia
- balance problems
Cerebral Hemisphere infarcts
- contralateral hemiplegia
- contralateral sensory loss
- homonymous hemianopia
- dysphasia
Brainstem infarct
- More severe symptoms including quadriplegia and lock-in syndrome
Lacunar infarct
- small infarcts around basal ganglia, internal capsule, thalamus and pons
- may result in pure motor, pure sensory, mixed signs or ataxia
What is Subdural Haemorrhage?
A collection of blood deep to the dural layer of the meninges
Blood is not within the substance of the brain and therefore is called an ‘extra-axial’ or ‘extrinsic’ lesion
Can be uni- or bi-lateral
How can Subdural Haemorrhage be classified?
Acute - most commonly caused by high-impact trauma, often underlying brain damage
Subacute
Chronic - present for weeks to month, rupture of the small bridging veins within subdural space that cause slow bleeding
Elderly and alcoholic patients are at risk since they have brain atrophy and therefore fragile and taut bridging veins
H&E of Subdural Haemorrhage
Key
- Headache
- Evidence of trauma
- N + V
- Low GCS
- Confusion
Other
- Loss of consciousness
- Seizure
- Loss of continence
- Focal neurological deficits
RF for Subdural Haemorrhage
- Recent trauma
- Anticoagulant use
- Alcoholism
- Advanced age
Investigations for Subdural Haemorrhage
1st
- Non-contrast CT head
- Shows fluid collection
- Crescenteric collection, not limited by suture lines
- Acute bleeds appear hyper dense, whereas chronic is hypo dense
- Large acute haematomas will cause ‘mass effect’ - midline shift or herniation
Management of Acute Subdural Haemorrhage
- If <10mm, <5mm midline shift and non-expansile without neurological dysfunction - conservative management
- If >10mm, >5mm midline shift, expansile, or neurological dysfunction - craniotomy
Antiepileptics if seizures/risk of seizures (phenytoin/levetiracetam)
Management of Chronic Subdural Haemorrhage
- Manage conservatively if small and no neurological deficit
- If patient is confused, has neurological deficit or severe image findings - surgical decompression with burr holes
Antiepileptics if seizures/risk of seizures (phenytoin/levetiracetam)
What is spinal cord compression?
An oncological emergency and effects up to 5% of cancer patients
Extradural compression accounts for majority of cases, usually due to vertebral body mets
More common in patients with lung, breast and prostate cancer
H&E of Spinal Cord Compression
- back pain - earliest and most common symptom, may be worse when prone or coughing
- lower limb weakness
- sensory changes : loss and numbness
- neurological signs dependent on level of lesion
- above L1 usually UMN signs in legs and a sensory level
- below L1 usually LMN signs in legs and perianal numbness
- tendon reflexes tend to be increased below level of lesion and absent at level of lesion
Investigations for Spinal Cord Compression
- Urgent whole spine MRI within 24hrs of presentation
Management of Spinal Cord Compression
- high dose oral dexamethasone
- urgent oncological assessment for consideration or radiotherapy or surgery
