Neuro Flashcards
Two cells that make up the brain
Neurons
Glial cells
Types of glial cells in the brain
Fibrous astrocytes
Protoplasmic astrocytes
Oligodendrocytes
Microglia
Ependymal cells
Gray matter covers
Interior of the SC
Exterior of the brain
White matter covers the
Exterior of the SC
Interior of the brain
Provides communication within the gray matter and to the outside
White matter
Where the actual processing occur
Gray matter
Where does the spinal cord exit
Foramen of Magnum
Where does the SC end?
L1 and L2
Parts of the forebrain
Diencephalon
Telencephalon
Hypothalamus
Function of the diencephalon
Relay motor and sensory signals to the cerebral cortex
Regulates sleep, consciousness, and awareness
Order of meninges from superficial to deep
Epidural space
Dura mater
Subdural space
Arachnoid membrane
Subarachnoid space
Pia mater
Brain
Potential spaces in the brain
Epidural space
Subdural space
What artery can be found in the Epidural space?
Middle Meningeal artery
What can be found in the Subdural space?
bridging veins that connect the dura mater to the arachnoid membrane
Only real space
Subarachnoid space
What can be found in the subarachnoid space?
Circle of Willis
Where does the middle meningeal artery pass through?
Grooves in the cranium
It is where the meninges enter
Falx Cerebri
What does the Tentorium Cerebelli do?
separates the brain stem and cerebellum from the diencephalon and cerebral cortex
Structures found above the Tentorium Cerebelli
Supratentorial
Structures found below the Tentorium Cerebelli
Infratentorial
Damages in the supratentorial structures result in
Contralateral effects
Damages in the infratentorial structures result in
Ipsilateral effects
The ventricles of the brain are lined by
Ependymal cells
What does the ventricles of the brain do?
Transport, produce, and remove CSF
The lateral ventricle contains the following
Frontal horn
Temporal horn
Posterior horn
What connects the lateral ventricle to the 3rd ventricle?
Foramen of Monroe
Where can the 3rd ventricle be located?
In the diencephalon; medial to thalamyn
What connects the 3rd and 4th ventricles?
Aqueduct of Sylvius
What is the roof and floor of the 4th ventricle?
Roof: Cerebellum
Floor: Pons
2 openings of the 4th ventricle
Luschka
Magendie
Area where the ventricular system is found
Area 1
Area where the sub arachnoid area is found
Area 2
How does the ventricular system communicate with the sub arachnoid space?
Through the foramen of Luschka and Magendie
CSF production per hr
20-24 mL
CSF production per day
400-500 mL
CSF excretion per hr
20-24 mL
Where is the CSF excreted?
Arachnoid granulations
Openings in the dura mater
Venous sinuses
What can be found in the Falx cerebri?
Superior and inferior sagittal sinuses
Clinical S/Sx of Hydrocephalus
Sunset eyes
Inc CSF
Ataxia
Dementia
How much blood can the brain accomodate?
150 mL
What structures does the ant circulation supply?
Cerebral hemispheres and deinephalon
Structures of the ant ciruclation
Internal Carotid artery (ICA)
What structures does the post circulation supply?
Brain stem and cerebellum
Occipital lobe and inferior temporal gyrus
Where does the MCA originate?
comes out laterally from the anterior circulation
What structure does the MCA supply?
lateral aspect of the cortex
Areas supplied by the superior division of the MCA
Frontal lobe
Area 4
Broca’s area
Areas 6-8
Areas 3, 1, 2
Areas supplied by the inferior division of the MCA
Parietal lobe
Superior and middle temporal gyrus
Areas 39 and 40
Areas 5-7
What are the smaller vessels that supply the diencephalon?
Candelabra branches of the MCA
Largest candelabra branches of the MCA
lenticulostriate or lateral striate artery
Arteries that supply all of the pons and midbrain
Deep penetrating branches of the Basilar artery
Where can the ACA be found?
medially in the cortex
What structure does the ACA loop around?
Corpus Callosum
What structures does the ACA supply?
Medial cortex (except occipital lobe and inferior temporal gyrus)
What artery supplies the occipital lobe and the inferior temporal gyrus?
PCA
What are the structures supplied by the PCA?
Occipital lobe and inferior temporal gyrus
Hippocampus
What structures does the PCA supply?
Occipital lobe
Inferior and medial temporal lobes
Thalamus
Midbrain
What brodmann’s areas does the MCA’s superior division supply?
Area 4
Broca’s area (44 and 45)
Areas 6-8
Areas 3, 1, 2
What effects does damage to the PCA do?
Cortical blindness
Visual propagnosia
Amnesia
The cortex if made up of what proteins?
Glycoproteins
What does the cortex do?
Origin of all voluntary movements
Conscious awareness
How is the cortex formed?
From neuroectodermal cells
Forms prosencephalon
Divides into 2 telencephalons
Matures into 2 cerebral hemispheres
What is the cortex made up of?
Gray matter with gyri and sulci
Fissure that divides the occipital and parietal lobes
Parieto-occipital fissure
Fissure that divides the occipital lobe
Calcarine fissure
Layers of the cortex (superficial to deep)
Molecular layer
External granular layer
External pyramidal layer
Internal granular layer
Internal pyramidal layer
Multiform layer
Components of the molecular layer
Axons and dendrites
Components of the external granular layer
Densely packed stellate cells
Small pyramidal cells
Components of the external pyramidal layer
Loosely packed stellate cells
Medium pyramidal cells
Components of the Internal granular layer
Densely packed stellate cells only
Components of the Internal pyramidal layer
Large pyramidal cells only (giant pyramidal cells of Betz)
Few stellate cells
Components of the multiform layer
Multiple sized pyramidal cells
Loosely packed stellate cells
Afferents of cortex layers 1-3
other regions of cortex and brain stem
Efferent of cortex layers 1-3
other regions of cortex (intra-cortical association function)
Afferent of cortex layer 4
other regions of cortex and brain stem
thalamus
Afferent of cortex layer 5
brain stem
Efferent of cortex layer 5
brain stem and spinal cord
Efferent of cortex layer 6
thalamus
This connects all the layers of the cortex except the 1st layer
Neuron of Martinotti
This enters deep into the white matter
Fusiform
Examples of association fibers of the crotex
Stellate cells
Martinotti cells
Cajal neurons
Examples of commisural fibers of the cortex
Corpus callosum
Anterior commissure hippocampal
What do projection fibers do?
Transmit data
Examples of projection fibers
Pyramidal cells
Brodmann area responsible for voluntary movements
4, 6, 8
Brodmann area responsible for proper response to stimuli
3, 1, 2
Brodmann area responsible for expression of speech
44
Primary motor area
4
Motor planning area
6 and 8
Function of the limbic lobe
core of emotions and responses
Structures of the Limbic lobe
Pre-frontal lobe
Amygdala
Cingulate cyrus
Nucleus basalis of meynert
Parahippocampus
Hippocampus
Insula of Reille
Floor of the frontal loble
Nucleus basalis of Meynert
3 major divisions of the Hippocampus
Subiculum
Ammons horn
Dentate gyrus
Where is the Parietal lobe located?
Posterior to the rolandic sulcus
What does the parietal lobe do?
Receive, collect, process, and interpret general stimulus
What structure of the brain sores all memory?
Inferior temporal gyrus
Where is the temporal lobe located?
Inferior to the Sylvian fissure
Where is the occipital lobe located?
posterior to the parietal lobe
Primary somatosensory area
3, 1, 2
Somatosthestetic association area
5 and 7
Integration area
39 and 40
Where is the primary visual area found?
beneath the calcarine fissure
Primary visual area
17
Visual association area
18 and 19
Primary auditory area
41 and 42
Auditory association area
22
Where is the auditory area found?
Superior to the temporal gyrus
What do you call the primary auditory association area?
Wernicke’s area
Functions of the left hemisphere
Language
Calculation
Left right orientation
Body part recognition
Reading
Functions of the right hemisphere
Singing
Visual spatial orientation
Drawing
Dressing
Recognition of the left side of the body
Ideomotor skills
Cortical dysfunction wherein the pt cannot express words
Broca’s aphasia (expressive/motor aphasia)
Cortical dysfunction wherein the pt cannot comprehend words spoken
Wernicke’s aphasia (receptive/sensory aphasia)
Cortical dysfunction wherein the pt fails to know something previously known
Agnosia
Cortical dysfunction wherein the pt fails to do something previously could do
Apraxia
The type of ectoderm that differentiates into the epidermis, nails, and hair
Surface ectoderm
The type of ectoderm that gives rise to the neural tube, neural crest which subsequently give rise to the brain
Neural ectoderm
Gives rise to the lining of the GIT and respiratory system
Endoderm
Gives rise to the axial skeleton, dermis, and muscle
Paraxial mesoderm
Gives rise to the gonads, kidneys, and urogenital structures
Intermediate mesoderm
Gives rise to the limb skeleton and muscular wall of gut tube
Lateral plate mesoderm
Stages of neural development
Neural plate
Neural groove/crest
Neural tube
What brain structure does the telencephalon develop into?
Cerebrum (Cortex, white matter, basal nuclei)
What brain structures are found in the diencephalon?
Thalamus
Hypothalamus
Epithalamus
What brain structure does the mesencephalon develop into?
midbrain
What brain structure does the Metencephalon develop into?
Pons
Cerebellum
What brain structure does the Myelencephalon develop into?
Medulla Oblongata
What forms the PCA?
Bifurcation of basilar artery
Small subcortical lesions less than 15 mm caused by occlusion penetrating an artery from a large cerebral artery
Lacunar syndrome
It is the off shoot of your vertebral arteries
Posterior Inferior Cerebellar Artery (PICA)
Where does PICA pass through
Between the medulla and cerebellum
What structures does the PICA supply?
Vermis
Central nuclei
Undersurface of cerebellar hemisphere
Medulla oblongata
Portions of choroid plexus and 4th ventricle
The most caudal large vessel arising from the basilar artery
Anterior Inferior Cerebellar Artery
What structures does the AICA supply?
anterior and inferior cerebellum
What structures does the penetrating branches of AICA supply?
Portions of the dentate nucleus and surrounding white matter
What structures does the smaller branches of AICA supply?
choroid plexus and 4th ventricle
What does occlusion of the AICA result in?
Nausea
Vomiting
Deafness
Facial paralysis
Cerebellar disturbances
Route of the Superior Cerebellar Artery
Encircles the brainstem near the pontomesencephalic junction and passes onto the superior surface of the cerebellum
What structures does the SCA supply?
Pons
Pineal gland
Superior medullary velum
What artery supplies the lateral medulla?
PICA
What CN nuclei are affected when the PICA is occluded?
CN 9-12 nuclei
What supplies the medial medulla
Anterior Spinal Artery
3 important structures in the diencephalon
Thalamus
Basal Ganglia
Internal Capsule
Thalamus is known as the
Little cortex
What type of area is the thalamus?
Gray matter area
Damage of the thalamus results in
Cerebral function loss
Thalamus can be found at
lateral to the 3rd ventricle
This structure of the brain chooses the muscle that will act on a certain movement. Moreover, it will give the muscle it’s role (antagonist, agonist, or synergist)
Basal Ganglia
White matter area in the Diencephalon
Internal Capsule
What does the Internal Capsule do?
Bring data in and out of the cortex
What does the Basal Ganglia do?
Plays an important role in the control and posture and voluntary movement
Does the Basal Ganglia have direct input/output to the spinal cord?
NO