Neuro Flashcards
guideline for seizures
NICE 2024 - revised
Management of epileptic seizure or management febrile seizure
Example medication seizures
- Lorazepam - 0.1mg/kg max 4
- Buccaneer - midazlam - only children
- Diazepam
if seizure over 15 minutes
1. IV levetiracetam 40mg/kg
2. IV phenytoin - 20mg/kg over 20 minutes
NICE revised 2022 - management epilepsy
Epilepsy - sodium valporate - NCIE 2022
Medication epilepsy
sodium valporate
NICE 2022
Priorities for seizures
- Environment - NHS 2023 - document length and symptoms - check identity cards - protect - cushion head, remove glasses - remove harmful objects - no retrain or in mouth
- Medication - more than 5 minutes or third in an hour 1. midazlam (children) (2. diazepam if prefered) 3. IV - lorazepam - sodium valporate
- medication over 15 minutes - levetiracetam and Phenytonin
- secure airway - intubate and ventilate
- reverse shock - fluid maintainance
- neuroprotect - therapy to prevent death or neural pathways
- Infusion of propofol until haemodnamically stable - anticonvolsant properties
NICE revised 2024 - Managing epileptic seizure
Symptoms of neuro deterioration
- hypoxia 0 ischamia
- hypotension (reduced perfusiono)
- hypertension (haemorrhage)
- cardiac dysrhymia - shock
- hyperthermia - blood flow and inflammation - increased metabolic demand
- raised ICP - alter GCS
- decrease sodium - cause oedema
- coagulation - haemorrhage
Reference neuro changes
NICE, 2019 - suspected neuro conditions
Symptoms of neuro changes
- altered consciousness
- decreased heart rate
- altered heart rhythms
- hypo/hypertensive
- temperture changes
- GCS changes
- pupil response or changed vision
- sudden onset headaches
- gait.balance changes
- muscle weakness and sensation changes
- nausea/vomiting
- photophobia
Priorities f neuro changes
NICE 2019
- Secure airway - O2 therapy
- Suction
- position - supine or side
- Investigations - ABG and cultures, ECG, CT, MRI
- medication for blood pressure - beta blockers and isotopes
- fluid balance - 0.9% saline - avoid dextrose and cause increased cerebral oedema increasing brains water content - visual swelling and cushing triad
- keep warm and monitor
- if pupils fixed give sodium chloride and mannitol
What is autonomic dryreflexia?
- caused most commonly by distended bowel/bladder
- a spinal cord lesion stopping noxious signals
- cause massive sympathetic reflex
- Causing widespread vasoconstriction of blood vessel
- hypertension
Symptoms of autonomic dysreflexia
- raised BP
- bradycardia
- pounding headache
- flushing
- sweating
- blotching above level of injury
- pale
- cold
- goosebumps below injury level
Priorities autonomic dysreflexia
- sit up - to return BP to normal
- loosen or remove tight clothing
- monitor BP every 2-5 minute
- Check bowel - constipation, hamorrrhoids and bladder for catheter kinks and obstructions
- Insert catheter
- systolic BP over 150 - start 10mg nifedipine sublingual or chewed r GTN spray 1-2 sprays - repeat 2-=30 min
ROYAL NATIONAL ORTHOPAEDIAC HOSPITAL - 2019
Reference GCS
Teasdale and Jennett (1974)
Symptom Intracranial Pressure Raise
NICE 2019
- altered consciousness
- confusion
- restless
- lethargy
- Headache
- Pupillary dysfunction
- motor and sensory deficits
- cranial nerve palsy
Late signs and symptoms of raised intracranial pressure
NICE 2019
- loss of consciousness eg, comatose
- bilateral dilated and fixed pupils
- altered vital signs
Priorities of raised intracranial pressure
- upright midline position - fluid drainage
- O2 therapy
- vital signs and escalate as appropriate
- avoid hyperthermia - use paracetamol to reduce metabolic demand
5, manage pain - Fluid resus - 500ml - 100ml 1st 10kg - 50ml 2nd 10kg - NICE 2016
- IV mannitol and 3% saline if pupils fixed - not under 12 year old - BNFC 2023 - BNF 2024
- CT and MRI
- GCS every 30 minutes -Teasdale and Jeannette 1974