Neuro Flashcards
frontal lobe functions
pre-frontal cortex - higher mental functioning
primary motor cortex - corticospinal
broaca area - speech
temporal lobe functions
primary auditory crotex
wernikes area - comprehension of speech
parietal lobe functions
primary somatosensory cotex
visual association cortex
somatosensory association cortex
occipital lobe functions
primary visual cortex
secondary visual cortex
layers of meninges
dura
arachnoid
pia
pyramidal tract function
voluntary muscle control
where does corticospinal tract decussate
medulla pyramids
pyramidal lesion signs
increased muscle tone hyperreflexia weakness clonus babinski+ hoffman+
extrapyramidal function
involuntary motor control
extrapyramidal lesion signs
parkinsonims
chorea
athetosis
dystonia
corticospinal tract lesion - what side
contralateral
cerebellar lesion signs
posture and gait
tremor and ataxia
nyastagmus
dysarthria
(ipsilateral)
UMN signs
no muscle wasting spasticity clonus preent brisk tendon reflexes babinski sign poor balance lack of coordination with movements
LMN signs
muscle wasting flacidity no clonus diminished/ansent reflexes waddling gait difficulty rising from chair
DCML pathway
discriminatory touch, pressure, vibration, conscious proprioception
ST pathways
fine touch, pain, temperature
DCML pathway lesion - what side
ipsilateral
ST pathway lesion - what side
contralateral
weak leg stroke - what vessel
anterior cerebral artery
weak arm and face stroke - what vessel
middle cerebral artery (most common)
eye problems stroke - what vessel
posterior cerebral artery
haemorrhagic stroke features
more likely to be conscious
headache
neurological defects sudden but more likely to be progressive
stroke scan
non-contrast CT
infarctions presentation on scan
wedge shaped
haemorrhage presentation on scan
dense
thrombylisis cut off
4.5 hours onset
confirmed occlusion of proximal anterior circulation
thrombectomy
secondary prevention stroke
statins
clopidogrel
generalised tonic-clonic treatment
SV
lamotrogine
absence seizure treatment
SV
ethosuximide
lamotrogine
parkinsons pathology
loss of dopaminergic neurons in the basal ganglia, most notably substantia nigra
parkinsons treatment
levodopa dopamin agnoists (cabergoline)
essential tremor presentation
strong family history
worse on intentional movement
reduce or absent at rest
essential tremor treatment
b-blockers
primidone
gabapentin
alcohol may help
huntingtons inheritance
autosomal dominant complete penetrance
huntingtons genes
defect on chromosome 4 on HTT gene
CAG trinucleotide repeat expansion
huntingtons treatment
supportive
antipsychotics
counselling family
MS pathology
chronic autoimmune T cell mediated
demyelination condition with axonal loss