neural + hormonal mechanisms

Question 1

Mann et al

Answer 1

gave patients dexfenfluramine (depletes serotonin). Used questionnaire to assess hostility levels. Drug associated with aggressive scores.

Question 2

Berman et al

Answer 2

gave patients placebo or paroxetine (enhances serotonin). Took part in lab game where electric shocks of various intensity given in response to provocation. Paroxetine gave fewer shocks.

Question 3

Gospic et al

Answer 3

exposed subjects to mild provocation. fMRI scans showed fast response by the amygdala when they acted aggressive.

Question 4

Denson et al

Answer 4

linked serotonin to firing of neurones so greater behavioural control. Decreased serotonin disrupts this leading to more aggression.

Question 5

Cocarro et al

Answer 5

suggests OFC activity reduced in disorders with aggression. Other explanations.

Question 6

Wagner et al

Answer 6

castrated mice + aggression dropped. Injected with testosterone and aggression rose.

Question 7

Dabbs et al

Answer 7

measured salivary testosterone in violent + non violent criminals. High levels of T were more violent.

Question 8

Carre + Mehta

Answer 8

high levels of T cause aggression but only when cortisol levels are low. Other explanations.

Question 9

Delgado

Answer 9

electrodes placed in limbic system of bull. Turned on or off to control aggression.

Question 10

Charles Whitman

Answer 10

shot 45 people but had tumour pressing against amygdala.