Neural Communication Flashcards
Luigi Galvani
Discovered electrical properties in the nervous system
Alessandro Volta
Replicated Galvani’s experiment, trying to dismiss that there was something special. He was right and determined that no electricity is conducted in the nervous system.
Diffusion
The distribution of ions in a medium. Spread of ions towards a uniform concentration. Reaching equilibrium is an equal spread of the ions.
Current
Is created by creating a difference of positive and negative charges across a barrier
Osmosis
The diffusion of molecules from a high concentration gradient to a low concentration gradient. Movement
Down a concentration gradient
Semi permeable membranes
Can create differences in diffusion in a medium. Pores of a certain size that allows some to pass through
Electrochemical attraction
Can influence the movement of ions towards one another. Gradients and forces which create a second force for ions to move to opposite charges.
Active transport
Carries molecules across a membrane usingprotien carriers. Dependent on energy being put into the system.
Plasma membrane
Allows axons to generate electrical potential. Allows for different concentrations inside and outside the cell.
How does resting potential happen?
Surrounding the neurons are countless Lons, there is a tiny excess of negative charged lons inside. [ all neurons at rest are negatively charged [- 5 to-100]] the resting potential depends on the type of neuron.
Semi - permable plasma membrane
Ion channels can pass different kinds of ions between them, semi-personable allows certain ions to enter or exist. Leaky nature cot plasma membranes causes it to remain open and positive charges can leave and enter as they please. Excess charges line up on the plasma membrane.
Action potential
Parts of an action potential needs energy to be inserted. 2-graded potential looking at sodium ions which causes a depolarization. 3-all or nothing channels go through a cycle of opening and closing. The more Na that rushes in the more depolarization. 4- sodium channels close but potassium channels remain open and allow k to leave the concentration gradient.
Triggering the action potential
Sensory activity: son channels open up when deflected by pressure, which allows sodium ions to enter. Depolarization: causes channels to open up in n all or nothing cascade.
Channel opens: external stimuli are transformed to a neural signal through sensory receptors. One after another they open and result in an electrical potential down an axon.
K+ channels open: causes a return to normal state.
Voltage gated sodium channels
The action potential rising phase occurs because the neuronal membrane contains voltage gated Na + channels that open in a regenerative manner. The action potential rising phase ends because the voltage gated Na + channels inactivate. Creates a Plato of action potential.The action potential falling phase occurs because the voltage gated k+ channels open (with a delay) in response to depolarization.
Speed of action potential probation
Estimation of 500 action potentials per second. Max. 1200 action potentials per sec. After voltage gated channels open and close, they can open up again, but they have to over come hyperpolarization.
Unmyelinated - slower conduction
Myelinated - faster conduction