Nervous System Physiology Part 8 Flashcards

1
Q

Where are anterior motor neurons located?

A

In the anterior horns of the spinal cord gray matter.

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2
Q

What are the two types of anterior motor neurons?

A

Alpha motor neurons and gamma motor neurons.

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3
Q

What do alpha motor neurons innervate?

A

Extrafusal muscle fibers.

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4
Q

What do gamma motor neurons innervate?

A

Intrafusal muscle fibers.

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5
Q

What are muscle spindles?

A

Encapsulated muscle fibers scattered throughout striated muscle.

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6
Q

How do anterior motor neurons compare in size to other neurons?

A

They are 50 to 100 percent larger.

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7
Q

What is the function of the ventral horn in the spinal cord?

A

It contains motor neurons responsible for movement.

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8
Q

What do alpha (α) motor neurons innervate?

A

Extrafusal skeletal muscle fibers.

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9
Q

What is a motor unit?

A

An alpha motor neuron and the muscle fibers that it innervates.

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10
Q

Why are alpha motor neurons called the “final common pathway” out of Central Nervous System ?

A

Because all neural influences on skeletal muscle converge on them, and they are the only route through which the CNS can affect skeletal muscle.

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11
Q

What do gamma (γ) motor neurons innervate?

A

Specialized intrafusal muscle fibers, which are part of muscle spindles.

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12
Q

What is the function of the muscle spindle?

A

To sense muscle length.

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13
Q

What is the function of gamma motor neurons?

A

To adjust the sensitivity of the muscle spindles.

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14
Q

What do gamma (γ) motor neurons innervate?

A

The polar regions of intrafusal fibers

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15
Q

What happens when gamma motor neurons are activated?

A

The central receptor region of the intrafusal fibers is stretched.

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16
Q

Where are muscle spindles located?

A

Throughout the belly of the muscle.

17
Q

What do muscle spindles do?

A

They send information to the nervous system about muscle length or rate of change of length.

18
Q

What is alpha-gamma coactivation

A

The simultaneous activation of gamma and alpha motor neurons to maintain tension in the muscle spindle during contraction.

19
Q

Why is alpha-gamma coactivation important?

A

: It prevents the central region of the muscle spindle from going slack during a shortening contraction, allowing continued sensory feedback.

20
Q

Where are Golgi tendon organs located?

A

: In the muscle tendons near their junction with the muscle.

21
Q

What do Golgi tendon organs detect?

A

Tendon tension or the rate of change of tension.

22
Q

What wraps around the collagen bundles in tendons?

A

Afferent nerve fibers from Golgi tendon organs.

23
Q

What activates the Golgi tendon organs?

A

Tension from muscle stretching or contraction that straightens collagen bundles and distorts receptor endings.

24
Q

When is the tendon stretched more: active contraction or passive stretch?

A

Tendon is stretched more during active contraction of the muscle.

25
Q

What are spinal reflexes?

A

Somatic reflexes mediated by the spinal cord, often without higher brain involvement.

26
Q

Name the three types of spinal reflexes.

A

1.The Stretch Reflex
2. The Tendon Reflex
3. The Withdrawal Reflex and Crossed-extensor Reflex

27
Q

How do Golgi tendon organs work?

A

Afferent nerve endings wrap around collagen bundles; when tension is applied, the collagen straightens and distorts the endings, activating the receptors.

28
Q

Does the brain play any role in spinal reflexes?

A

Yes, the brain is “advised” of most spinal reflex activity and can facilitate, inhibit, or adapt it.

29
Q

What triggers the stretch reflex?

A

Stretching of muscle spindles activates sensory neurons, which send signals to the spinal cord.

30
Q

What happens when sensory neurons of the stretch reflex reach the spinal cord?

A

They synapse with motor neurons that excite the extrafusal muscle fibers of the stretched muscle, causing contraction.

31
Q

What is the function of the stretch reflex?

A

: It causes reflexive muscle contraction to resist further stretching.

32
Q

What initiates the knee-jerk reflex?

A

Tapping the patellar ligament stretches the quadriceps and excites its muscle spindles.

33
Q

What does a positive knee-jerk reflex indicate?

A

That sensory and motor pathways between the muscle and spinal cord are intact and it shows spinal cord excitability.

34
Q

What happens during the knee-jerk reflex after the quadriceps are stretched?

A

Afferent impulses travel to the spinal cord.
2. Motor neurons send activating impulses to quadriceps (causing contraction).
3. Interneurons inhibit motor neurons to hamstrings (preventing resistance to movement).

35
Q

How does the state of spinal motor neurons affect the reflex response?

A

Highly facilitated neurons cause a strong reflex, while high inhibitory input may prevent the reflex entirely.