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CPT > NERVOUS SYSTEM PHARMACOLOGY > Flashcards

NERVOUS SYSTEM PHARMACOLOGY Flashcards

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NASM ® CPT flashcards
1
Q

Diazepam (valium)

Lorazepam

A

Antiolytics (anti anxiety)

Increase GABA activity

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2
Q

Cyclizine

A 
Nausea & vomiting 
H1 antagonist (histamine receptor)
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3
Q

Domperidone

Metoclopramide

A

Nausea & Vomiting
D2 antagonist (antidopaminergic)
(metoclopramide also 5HT3 antagonist)

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4
Q

Ondansetron

A

Nausea & Vomiting (typically chemo and surgery induced)

5HT3 antagonist

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5
Q

Hyoscine hydrobromide

A

Nausea & Vomiting

Muscarinic antagonist

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6
Q

Aprepitant

A

Nausea & Vomiting

Neurokinin-1 (NK1) antagonist

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7
Q

Chlorpromazine

Haloperidol

A

Antipsychotic
D2 receptor antagonism (antidopaminergic)
Can be used as antiemetic

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8
Q

Aspirin

A

Analgesic

Inhibition of prostaglandin production

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9
Q

Paracetamol

A

Analgesic

COX-2 inhibition in spinal cord

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10
Q 
Buprenorphine 
Codeine 
Diamorphine 
Methadone 
Morphine 
Tramadol
A

Analgesics

Opioid receptor agonists

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11
Q

Acetylcystine

A

Paracetamol overdose

Glutathione donation

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12
Q

Naloxone

A

Opioid receptor antagonist

Block opioid effects (e.g. overdose)

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13
Q

Carbamazepine
Lamotrigine
Phenytoin

A

Anti-epileptic

Na channel blockers

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14
Q

Sodium Valporate

A

Anti-epileptic

Indirect increase in GABA synthesis

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15
Q

Levetiracetam

A

Anti-epileptic

unclear MOA, presynaptic Ca2+ blocking activity

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16
Q 
Amantadine 
Apomorphine 
Ropinirol 
Rotigotine 
Levodopa 
Co-careldopa* (Sinemet)
Co-beneldopa* (Madopar)
A

Dopamine receptor agonists
Dopamine precursors

*contain levodopa and DOPA decarboxylase inhibitor

17
Q

Ropinirole
Pramipexole
Rotigotine

A

Dopamine receptor agonists

18
Q

Selegiline

Rasagaline

A

Monoamine oxidase type B inhibitors

19
Q

Entacapone

A

COMPT inhibitor

20
Q

Stalevo

A

L-Dopa + COMPT inhibitor + Dopa decarboxylase inhibitor

21
Q

Procyclidine

Trihexypenidydyl

A

Anticholinergics

22
Q

Pyridoigmine

Neostigmine

A

Acetylcholinesterase inhibitors

23
Q

Bupivacaine
Lidocaine
Ropivacaine

A

Local Anaesthetics

CPT (9 decks)

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