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CPT > CVS PHARMACOLOGY > Flashcards

CVS PHARMACOLOGY Flashcards

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NASM ® CPT flashcards
1
Q

Bendroflumethiazide

Indapamide

A

Thiazides

Inhibit Na/Cl co-transporter in DCT

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2
Q

Bumetanide

Furosemide

A

Loop diuretic

Inhibition of Na/K/2Cl (NKCC) co-transporter in DCT

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3
Q

Amiloride

A

Potassium sparing diuretic

Block ENaC

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4
Q

Spironolactone

A

Aldosterone antagonist

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5
Q

Flecainide

Lidocaine

A

Class I antiarrhythmic

Na channel blockers

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6
Q

Bisoprolol

A

Class II antiarrhythmic

beta adrenoceptor blockers

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7
Q

Amiodarone

Sotalol

A

Class III antiarrhythmic

K channel blockers

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8
Q

Diltiazem

Verapamil

A

Class IV antiarrhythmic

Ca channel blockers

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9
Q

Adenosine

A

K current activation in SAN and AVN

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10
Q

Atropine

A

Muscarinic antagonist

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11
Q

Digoxin

A

Inhibition of Na/K/ATPase

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12
Q

Ivabradine

A

Inhibition of If (funny current) in SAN

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13
Q

Labetalol

Propranolol

A

Beta adrenoceptor blockers

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14
Q

Doxazosin

A

Alpha adrenoceptor blockers

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15
Q

Lisinopril

Ramipril

A

ACE inhibitors

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16
Q

Candesartan

Losartan

A

Angiotensin Receptor blockers (ARB)

17
Q

GNT spray

Isosorbide mononitrate

A

Nitrates

Soluble guanylyl cyclase activation - elevate cGMP - vasodilation

18
Q

Amlodipine
Diltiazem
Verapamil

A

Calcium channel blockers

L-type- tissue selective

19
Q

Warfarin

A

Vit K antagonist

Vit K epoxide reductase inhibition

20
Q

Unfractionated heparin

A

Inhibition of active clotting factors - XIIa, XIa, IXa, Xa, and II (thrombin)

21
Q

Dateparin

Enoxaparin

A

LMWH

Inhibition of active clotting factor Xa

22
Q

Fondaparinux

A

Synthetic pentasaccharide

Inhibition of active clotting factor Xa

23
Q

Apixaban

Rivaroxaban

A

Direct acting oral anticoagulant

Inhibition of active clotting factor Xa

24
Q

Argatroban

Dabigatran

A

Direct thrombin inhibitors

Inhibition of active clotting factor IIa (thrombin)

25
Q

Protamine sulphate

A

Heparin reversal

binds to heparin –> inactive

26
Q

Vit K1

Prothrombin complex concentrate

A

Warfarin reversal

Promotes production of clotting factors

27
Q

Aspirin

A

Antiplatelet

Reduction of TXA2 synthesised by COX-1 inhibition

28
Q

Dipyridamole

A

Antiplatelet
Phosphodiesterase inhibitor
Inhibition of adenosine reuptake in platelets

29
Q

Clopidogrel

Ticagrelor

A

Antiplatelet

P2Y12 receptor antagonists

30
Q

Abciximab

A

Antiplatelet

Irreversible binding of GPIIb/IIIa receptors

31
Q

Alteplase

Reteplase

A

Fibrinolytic

Binds to and activates plasmin to plasminogen

32
Q

Tranexamic acid

A

Anti-fibrinolytics

Inhibits activation of plasminogen from plasmin

33
Q

Atorvastatin

Simvastaton

A

Statins (lipid lowering)
Inhibit rate limiting step of mevalonate pathway
HMG-CoA reductase inhibitors

34
Q

Fenofibrate

A

Fibrates (lipid lowering)

PPAR-alpha activation

35
Q

Ezetimibe

A

Cholesterol absorption inhibitors (Lipid lowering)

NPC1L1 transporter inhibition

36
Q

Niacin

A 
Nicotinic acid (lipid lowering) 
Inhibition of diacylglycerol acetyltransferase -2
37
Q

Alirocumab

Evolocumab

A 
PCSK9 inhibitors (Lipid lowering) 
Monoclonal antibodies that inhibit the PCSK9 enzyme

CPT (9 decks)

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