Nervous System Flashcards

1
Q

Give 4 differences between motor neurones and sensory neurones?

A

Motor Neurones have:

  • Long axon
  • No receptor
  • Has dendrites
  • Many short dendrons
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2
Q

What is a dermatome?

A

an area of skin that is supplied by a single spinal nerve

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3
Q

What is a myotome?

A

Group of muscles innervated by a single spinal nerve

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4
Q

What is a NMJ?

A

Chemical synapse between a motor neurone and a muscle fibre

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5
Q

What are biomarkers?

A

naturally occurring molecules, genes or characteristics by which a particular disease can be identified

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6
Q

What is a biomarker of spina bifida in the CSF?

A

Increase in CSF proteins

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7
Q

What is spina bifida?

A

Neural tube disorder that causes the incomplete closing of backbone and membranes around spinal cord

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8
Q

What 2 compounds can be taken to treat/prevent spina bifida?

A

Folic acid and Inositol

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9
Q

What is hydrocephalus?

A

accumulation of CSF in the brain causing increased cranial pressure

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10
Q

Give 3 causes of hydrocephalus?

A

spina bifida
meningitis
brain tumour

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11
Q

define odds ratio:

A

Quantifies the strength of association between 2 events

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12
Q

define relative risk?

A

ratio of the probability of an event occurring in the exposed group versus the probability of the event occurring in the non-exposed group

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13
Q

define confidence interval?

A

a range of values so defined that there is a specified probability that the true value lies within it

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14
Q

What regions are the spine organised into?

A

Cevrical
Thoracic
Lumbar
Saccrum + Coccyx

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15
Q

what adrenergic receptor is present on the heart, and what pathway is it?

A

B1, G-alpha-S

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16
Q

What adrenergic receptor is found on bronchial smooth tree and what signalling pathway does it use?

A

B2, G-alpha-S

17
Q

What adrenergic receptors are present on bladder smooth muscle?

A

B2 and B3

18
Q

What affect does the G-alpha-S signalling pathway have on smooth muscle?

A

Relaxes

19
Q

What is calsequestrin?

A

calcium binding protein that acts as a calcium buffer in the SR (after contraction)

20
Q

What is the function of the SERCA pump?

A

Uses ATP to pump calcium back into SR against its concentration gradient