nervous system Flashcards
functions
- control internal environment
»> coordinated with the endocrine system - voluntary control of movement
- spinal cord reflexes
- assimilation of experiences necessary for memory and learning
central nervous system
- brain & spinal cord
peripheral nervous system
- neurons outside CNS
- sensory division
- motor division
sensory division
afferent fibers transfer impulses from receptors to CNS
motor division
efferent fibers transmit impulses from CNS to effector organs
neurons
- body (soma)
- dendrites
- axons: at the ends are axon terminals
» these have synaptic knobss which house neurotransmitters
communicate via electrical impulses
multiple sclerosis patients (MS)
neurological disease that destroys myelin sheaths of axons
- occurs due to immune attack in myelin
- exact cause not known - defects in several genes
- results in progressive loss of nervous system function
- fatigue, muscle weakness, poor motor control, loss of balance, mental depression
exercise training improves both functional capacity and quality of life
electrical activity in neurons
neurons are excitable cells
» irritability: ability to respond to a stimulus and trigger a neural impulse
» conductivity: transmission of the impulse along the axon
resting membrane potential
negative charge inside cells at rest
> -5 to -100 mv across all cell types
> -40 to -75 mv in neurons
charge determined by:
Permeability: of plasma membrane to ions
> diff in ion concentrations across membrane
- Na+, K+, & Cl- play most important role
maintained by sodium-potassium pump
> potassium tends to diffuse out of the cell
- Na+/K+ pump moves 2 K+ in and 3 Na+ out
neurons transmit messages via action potential
- occurs when a stimulus of sufficient strength depolarizes the neuron
> opens Na+ channels, and Na+ diffuses into cell
> inside becomes more positive
repolarization
return to resting membrane potential
> K+ leaves the cell rapidly
> Na+ channels close
all-or-none law
once a nerve impulse is initiated, it will travel the length of the neuron
synapse
small gap between presynaptic neuron and postsynaptic neuron
neurotransmitter
- chemical messenger released from presynaptic membrane
- binds to receptor on postsynaptic membrane
- causes depolarization of postsynaptic membrane
excitatory postsynaptic potentials (EPSP)
can promote neural depolarization in two ways:
1.) temporal summation: summing several EPSPs from one presynaptic neuron
2.) spatial summation: summing EPSPs from several different presynaptic neurons
inhibitory postsynaptic potentials (IPSP)
causes hyperpolarization (more negative resting membrane potential)
neurons with a more negative membrane potential resist depolarization
neurotransmitters of interest for PA & exercise
1.) epinephrine & norepinephrine
2.) dopamine
3.) serotonin
4.) acetylcholine (AcH)
nociceptors
pain receptors
thermoreceptors
temperature receptors
chemoreceptors
respond to water-soluble and lipid-soluble substances dissolved in body fluids
mechanoreceptors
sensitive to stimuli that distort their plasma membranes
proprioceptors
-receptors that provide CNS with info about body position
- located in joints and muscles
kinesthesia
- conscious recognition of the position of body parts
- recognition of speed of limb movement
free nerve endings
- most abundant type of joint proprioceptors
- sensitive to touch and pressure
- initially strong stimulated, then adapt
(JP)