Nervous System Flashcards
Functions of the Nervous System
- Acts as the body’s communicating system and coordinates body activities
- Builds up a background of experience (memory) by recording and relating certain stimuli and responses. This is called learning.
Properties of Neurons:
- Can live and function for a long time
- They do not divide- fail to go under mitosis after birth
- High metabolic rate- require abundant oxygen and glucose
Constitues one of the cells of the nervous tissue and has the property of receiving and transmitting nervous impulse
Neurons
any of the filamentous bands of nervous tissue that connect parts of the nervous system with the other organs, conduct nervous impulses, and are made up of axons and dendrites together with protective and supportive structures
Nerves
Soma or cell body parts
Nissl bodies, Golgi Apparatus, Microfilament/Neurotubules and Mitochondria
discrete granular bodies of variable size that are seen in the soma and the dendrites, but not in the axon, and are composed of RNA and used for protein synthesis
Nissl bodies
important in packaging peptides and proteins (including neurotransmitters) into vesicles.
Golgi Apparatus
system of transport for materials within a neuron and may be used for structural support
Microfilaments or Neurotubules
small extensions from the cell body that receive information and carry the impulses toward the cell body
dendrites
long section, carries impulses away from the body
axon
Axon is made up of..
Axon hillock, schwann cell, myeline sheath, nodes of ranvier, neurilemma and axon terminal
the part of the axon where it emerges from the soma
axon hillock
forms the myeline sheath consisting of the inner spiral layers from which the protoplasm has been squeezed out
schwann cell
fat like layered insulation surrounding the axon interrupted at intervals called ________
myelin sheath; node of ranvier
gaps in the insulation
nodes of ranvier
sheath of schwann- the plasma membrane surrounding a schwann cell
neurilemma
contains neurotransmitters that are released to communicate with target neurons
Axon terminal
two processes extending from the cell body; axon and dendrite are on opposite sides
bipolar neurons
dendrite and axon emerging from one process
unipolar cell
have many processes that extend from the cell body. Each neuron has only one axon
multipolar neurons
provide structural integrity and functional support to the nerves
neuroglia or glial cells
Functions of the neuroglial
- Forms Myeline sheath
- Protects neurons via phagocytosis
- Regulates the internal environment of neurons in the CNS
- Helps in the regeneration of the cell
4 types of nerve fibers
unmyelinated without neurilemma, unmyelinated with neurilemma, myelinated without neurilemma, myelinated with neurilemma
3 classifications of neurons
Sensory (afferent), motor (efferent), interneurons
sends information from sensory receptors TOWARD the CNS
sensory (afferent) neurons
sends information AWAY from the CNS to muscles or glands
motor (efferent) neurons
send information BETWEEN sensory neurons and motor neurons. Most are located in the CNS
interneurons
substance that transmits nerve impulses across a synapse
neurotransmitters
Actions on other Neurons
Excitatory neurons, inhibitory neurons, modulatory neurons
Excite their target; neurotransmitter is _____
excitatory neurons; Acetylcholine (ACH)
Inhibit their target neurons; mostly interneurons; neurotransmitters are ______
inhibitory neurons; GABA and glycine
evoke more complex effects; neurotransmitters are _________
modulatory neurons; Dopmaine, ACH, Serotonin etc.
Excitatory neurons….
- Increase membrane permeability
- Increases chance for threshold to be achieved
Inhibitory neurons…
- Decrease membrane permeability
- decrease chance for threshold to be achieved
nerve endings which are specialized for receiving certain stimuli
receptors
3 receptors
Exteroreceptor, Interoreceptor, Proprioceptor
Receive sensations of touch, pain, temp., vision, and hearing from sources outside the body
Exteroreceptors
Receive visual sensations such as hunger, thirst and visceral pain from sources arising inside the body
Interoreceptors
located in muscles, tendons, and joints, which receive sensations of position, movement, deep pressure and balance
proprioceptors
structures which carry out the motor activities
effectors
two types of effectors
somatic and visceral
effector located in skeletal muscles
somatic effectors
effector located in smooth muscles, heart, and secretory glands
visceral effectors
propagated disturbance along a nerve cell. Movement of ___________ along a nerve cell, and is conducted along the axon to its terminal
impulse; action potential
Speed of an impulse is determined by…
- diameter of the axon (greater = faster)
- Myelinated neurons conduct faster than unmyelinated neurons
Self regenerating wave of electrochemical activity that allows nerve cells to carry a signal over a distance
action potential
Action potential is also known as ________. (The rapid rising and falling of the action potential form a sharp spike called the_______)
nerve impulses/spikes; spike potential
Membrane potential in cells are determined by…
- The concentration of ions on the inside and outside of the cell
- The permeability of the cell membranes to those ions through specific ion channels
- The activity of electrogenic pumps that maintain the ion concentrations across the membrane.
Two ions that contribute to membrane potential
Sodium and Potassium
How many ions of K and Na get pumped in a neuron?
3 Na to the outside; 2 K to the inside
What is the reason why there is a higher concentration of sodium on the outside than the inside
Active transport mechanism named the Sodium-Potassium Pump
That which can evoke or elicit action (response) in a muscle, nerve, or any other excitable tissue, or cause an augmenting action on any function or metabolic processes.
Stimuli
Stimulus that is strong enough to achieve an action potential
Threshold stimulus
The minimum intensity of a stimulus needed to achieve an action potential
Threshold intensity
The potential (voltage) at which action potential is initiated. For excitable membrane, this is ________ than the resting membrane potential
Threshold potential; 15 mv less
Mechanism of Action Potential
- When at rest, the cell membrane of the neuron allows certain ions to pass through while preventing/restricting the movement of other ions.
- The stimulus which could be electric, chemical, or mechanical causes the sodium gates/channels to open.
- All the positively-charged sodiums rush in causing the membrane to be positive on the inside than the outside
- The sodium channels briefly open then close
- Potassium channels then open, and because there is more potassium inside the membrane than the outside, positively-charged potassium ions diffuse out.
- As these positive potassium ions go out, the inside of the membrane once again becomes negative with respect to the outside and the resting membrane potential is restored.
The membrane potential is less negative than the resting level
Depolarization
Return of the membrane to its resting level
Repolarization
The membrane potential is more negative than the resting level
Hyperpolarization
Jumping of the impulse from one node of Ranvier to the next
Saltatory Conduction
Junction between two communicating neurons
The Synapse
Synaptic transmission
Dendrite -> cell body -> axon -> synapse -> dendrite -> cell body -> axon
impulse travels from neuron to neuron
nerve pathway
to complete the signal, a ______ is released at the gap to _______ the next neuron
neurotransmitter; signal
Neuron approaching the synapse. It send ______________ signals to the postsynaptic neuron.
Presynaptic neuron; electrical or chemical
Receives the signals from the presynaptic neuron and produces either an _________________ response
postsynaptic neuron; inhibitory or excitatory
How is an impulse transmitted across a synaptic cleft?
- Action potential reaches the axon terminal
- Voltage gated Ca+2 channel opens -> influx of Ca+2
- Ca signals the release of neurotransmitters
- Neurotransmitters are released into the synaptic cleft and diffuse to post-synaptic terminals
- Neurotranmitter binds to receptor in post-synaptic membrane
- Causes Na+ channels to open if threshold potential is reached
- An action potential is initiated
- Neurotransmitter is broken down by specific enzymes in the synaptic cleft
2 Main neurotransmitters
Acetycholine (Ach) and Noradrenaline
-released by all motor neurons, activating skeletal muscles
-involved in parasympathetic nervous system (relaxing responses)
Acetycholine (Ach) (Cholinergic synapse)
- involved in the sympathetic nervous system (fight or flight response)
Noradrenaline (Adrenergic synapse)
What is under the CNS
Brain and spinal cord
What is under the PNS
motor neurons and sensory neurons
what is under motor neurons
somatic and autonomic nervous system
what is under autonomic nervous system
sympathetic division and parasympathetic division
receives and posses sensory information, initiates responses, stores memories, generates thoughts and emotions
brain
conducts signals to and from the brain, controls reflex activities
spinal cord
CNS to muscles and glands
motor neurons
Sensory organs to CNS
sensory neurons
Controls voluntary movements
somatic nervous system
Controls involuntary movements
autonomic nervous system