Nervous Flashcards
• branch of
medicine that
specializes in
diagnosing &
treating
nervous system
disorders
NEUROLOGY
• the means of communication
of the nervous system
NERVE IMPULSE
• or “action potential “ or
“electrical signal“
NERVE IMPULSE
FUNCTIONS of the
Nervous System
• Sensory receptor
monitors stimuli or changes in
the body’s internal & external
environment
sends its gathered information
or input to the brain & spinal
cord
SENSORY FUNCTION
• the analysis & interpretation of
sensory input & making decisions
consciously or unconsciously
INTEGRATION
FUNCTIONS of the
Nervous System
• may produce any of the ff.:
✓ immediate response
✓ information stored as
memory
✓ ignoring of the input
INTEGRATION
•major
organs for
processing
sensory input
& initiating
responses
BRAIN AND SPINAL CORD
•specific areas in
the brain &
spinal cord w/c
process particular
inputs
CONTROL CENTERS
FUNCTIONS of the
Nervous System
• sending of commands or motor
outputs to activate effector organs:
✓ voluntary or conscious control:
skeletal muscles
✓ involuntary or unconscious
control: smooth & cardiac
muscles, glands
MOTOR FUNCTION
DIVISIONS of the Nervous
System
✓ includes the brain & spinal
cord, w/c occupies the cranial &
vertebral cavities, respectively.
CENTRAL NERVOUS SYSTEM
DIVISIONS of the Nervous
System
✓ comprise sensory receptors &
all nerves outside the CNS
✓ relays information to & from the
CNS
PERIPHERAL NERVOUS SYSTEM
DIVISIONS of the Nervous
System
2. Functional Divisions of the PNS
✓ conveys impulses to the CNS
from sensory receptors located
in various parts of the body
SENSORY OR AFFERENT DIVISION
- Functional Divisions of the PNS
a) Sensory or Afferent division
✓ associated w/ muscles, joints,
& skin
SOMATOSENSORY RECEPTORS
- Functional Divisions of the PNS
a) Sensory or Afferent division
✓ found in the ear, eye, nose, &
tongue
SPECIAL SENSE RECEPTORS
DIVISIONS of the Nervous
System
2. Functional Divisions of the PNS
a) Sensory or Afferent division
✓ found in the internal organs
AUTONOMIC/VISCERAL SENSORY RECEPTORS
DIVISIONS of the Nervous
System
2. Functional Divisions of the PNS
✓ carries impulses from the CNS to
effector organs (muscles &
glands)
✓ subdivided into (1) somatic & (2)
autonomic divisions
MOTOR OR EFFERENT DIVISION
DIVISIONS of the Nervous
System
2. Functional Divisions of the PNS
b) Motor or Efferent division
✓ regulates activities under
voluntary control
✓ initiates skeletal muscle
actions
SOMATIC NERVOUS SYSTEM
DIVISIONS of the Nervous
System
2. Functional Divisions of the PNS
b) Motor or Efferent division
✓ regulates involuntary actions
(e.g. heart rate, BP, body temp.)
✓ involves cardiac muscle, smooth
muscle & glandular tissue
AUTONOMIC NERVOUS SYSTEM (ANS)
DIVISIONS of the Nervous
System
2. Functional Divisions of the PNS
b.2. Autonomic nervous system (ANS)
✓ has two (2) subdivisions:
supports “fight-or-
•flight” responses or emergency
actions
SYMAETHETIC NERVOUS SYSTEM
DIVISIONS of the Nervous
System
2. Functional Divisions of the PNS
b) Motor or Efferent division
b.2. Autonomic nervous system (ANS)
✓ has two (2) subdivisions:
•supports “rest-and-
digest” activities
PARASYMPATHETIC NERVOUS SYSTEM
TYPES of CELLS in Nervous
Tissue
NEURON
NEUROGLIA
THE NEURON Parts
DENDRITE
CELL BODY
AXON
• or “glia “ or “glial cells”
• collective term for
supporting cells of the
nervous system
• outnumber the neurons
• found in both CNS & PNS
NEUROGLIA
• Support, protect & nourish neurons
• Divide by mitosis
• Do NOT transmit nerve impulses
CHARACTERISTICS OF
NEUROGLIA
NEUROGLIA OF THE CNS
• star-shaped cells
• most abundant glial cells of
the CNS
ASTROCYTES
NEUROGLIA OF THE CNS
• functions:
✓ hold neurons in place
✓ regulate exchange of
substances to & from CNS
neurons
ASTROCYTES
NEUROGLIA OF THE CNS
• functions:
✓ form the blood–brain
barrier to protect neurons
from harmful chemicals
ASTROCYTES
NEUROGLIA OF THE CNS
• spider-like cells
• phagocytes of CNS
• smallest & least abundant
neuroglia of the CNS
MICROGLIA
NEUROGLIA OF THE CNS
• functions:
✓ protect against
microorganisms
✓ clear away debris of dead
cells
MICROGLIA
NEUROGLIA OF THE CNS
• or “ependyma”
• ciliated cells
• line the fluid-filled cavities
of CNS (ventricles of brain
& central canal of spinal
cord)
EPENDYMAL CELLS
NEUROGLIA OF THE CNS
• function: produce
cerebrospinal fluid (CSF) &
assist in its circulation
EPENDYMAL CELLS
NEUROGLIA OF THE CNS
• cells whose branches wrap
around axons of CNS
neurons
OLIGODENDROCYTES
NEUROGLIA OF THE PNS
• surround all axons in the
PNS
SCHWANN CELLS
NEUROGLIA OF THE PNS
• functions:
✓ make myelin sheath of
PNS neurons
✓ aid in axon repair
SCHWANN CELLS
NEUROGLIA OF THE PNS
a. SCHWANN CELLS
•the sheath
around PNS axons formed
by the cytoplasm & nuclei
of Schwann cells; is
essential for the
regeneration of damaged
PNS neurons
NEUROLEMMA
NEUROGLIA OF THE PNS
• functions:
✓ provide support &
nutrition
✓ regulate exchange of
substances to & from PNS
neurons
SATELLITE CELLS
• Amitotic & have limited
ability to repair themselves
• High metabolic rate
PROPERTIES OF NEURONS
PROPERTIES OF NEURONS
•ability to respond to a stimulus
& convert it into a nerve impulse
IRRITABILITY OR EXCITABILITY
PROPERTIES OF NEURONS
•ability to transmit the impulse to
other neurons, muscles or glands
CONDUCTIVITY
Parts & Related Structures of NEURONS
•or “soma”
• contains the nucleus & other
cellular organelles (rough ER,
mitochondria, etc.)
CELL BODY
Parts & Related Structures of NEURONS
• metabolic center of the
neuron
• any part of the neuron
detached from the soma will
degenerate
CELL BODY
Parts & Related Structures of NEURONS
• branches of a neuron
• also called “nerve fibers”
• collective name for the axon
& dendrites
PROCESS
Parts & Related Structures of NEURONS
• shorter, numerous branches
of the neuron
• together w/ the cell body, are
the receiving or input parts
of the neuron
DENDRITES
Parts & Related Structures of NEURONS
• longer branch of the neuron
• conduct nerve impulses to
another neuron or an
effector organ
AXON
Parts & Related Structures of NEURONS
• site where impulses begin
AXON HILLOCK
Parts & Related Structures of NEURONS
• ending of axon where it
meets another cell
AXON TERMINAL
Parts & Related Structures of NEURON• a many-layered covering
composed of lipid & protein
• insulates the axon of a
neuron & increases the speed
of nerve impulse conduction
MYELIN SHEATH
Parts & Related Structures of NEURONS
• axons with a myelin sheath
are said to be myelinated &
those without it are said to
be unmyelinated
MYELIN SHEATH
Parts & Related Structures of NEURONS
• are gaps in the myelin sheath
that appear as intervals along
the axon
NODE OF RANVIER
Parts & Related Structures of NEURONS
• the functional junction bet.
two neurons or bet. a neuron
& an effector, such as a
muscle or gland
SYNAPS
Parts & Related Structures of NEURONS
• presynaptic neuron: the
neuron before the synapse
• postsynaptic neuron: the
neuron after the synapse
SYNAPSE
Parts & Related Structures of NEURONS
• tiny sacs contained in the
axon terminals that store
neurotransmitters
SYNAPTIC VESICLES
Parts & Related Structures of NEURONS
• molecules released from
synaptic vesicles w/c serve as
the means of communication
at a synapse (since neurons
do not actually touch each
other)
NEUROTRANSMITTERS
FUNCTIONAL CLASSIFICATION
OF NEURONS
• or “afferent neurons “
• carry impulses from sensory
receptors to the CNS
• can be SOMATIC or
AUTONOMIC
SENSORY
FUNCTIONAL CLASSIFICATION
OF NEURONS
• or “efferent neurons “
• carry impulses from the
CNS to effector organs
• can be SOMATIC or
AUTONOMIC
MOTOR
FUNCTIONAL CLASSIFICATION
OF NEURONS
• or “association neurons “
• only found in the CNS
• connect motor & sensory
neurons & integrate
impulses
INTERNEURONS
COLLECTIONS of Nervous Tissue
• clusters of cell bodies of
neurons within the CNS
• called a “center” if with the
same function
NUCLEI
COLLECTIONS of Nervous Tissue
• singular: ganglion
• clusters of cell bodies of
neurons in the PNS
GANGLIA
COLLECTIONS of Nervous Tissue
• bundles of nerve fibers in
the CNS
TRACTS
COLLECTIONS of Nervous Tissue
• bundles of nerve fibers in
the PNS
NERVES
COLLECTIONS of Nervous Tissue
• dense collection of
myelinated fibers (tracts)
in the CNS
WHITE MATTER
COLLECTIONS of Nervous Tissue
• dense collection of
unmyelinated
fibers & nuclei in
the CNS
GRAY MATTER
Connective Tissue Components of Nerves
• encloses the entire nerve
EPINEURIUM
Connective Tissue Components of Nerves
• covers bundles of axons
called nerve fascicles
PERINEURIUM
Connective Tissue Components of Nerves
• covers each axon in one
nerve fascicle
ENDONEURIUM
TYPES OF CONDUCTION
• occurs in unmyelinated axons
• each adjacent segment of the
plasma membrane
depolarizes & generates an
action potential that
depolarizes the next patch of
the membrane
CONTINUOUS CONDUCTION
TYPES OF CONDUCTION
• a faster type of conduction
that occurs in myelinated
axons
• the nerve impulse literally
jumps or leaps, from node to
node along the length of the
fiber
SALTATORY CONDUCTION
FACTORS Affecting Nerve
Impulse Conduction
• Axons with large diameters
conduct impulses faster than
those with small diameters
DIAMETER OF THE AXON
FACTORS Affecting Nerve
Impulse Conduction
• Myelinated axons conduct
impulses faster than
unmyelinated axons
PRESENCE OF MYELIN SHEATH
FACTORS Affecting Nerve
Impulse Conduction
• Axons conduct impulses at
higher speeds when warmed
and at lower speeds when
cooled
TEMPERATURE
FACTORS Affecting Nerve
Impulse Conduction
• Continuous pressure → blood
flow → delivery of O2 &
nutrients → impulse
conduction
PRESSURE
CLASSIFICATION of
Neurotransmitters
EXCITATORY
INHIBITORY
MAJOR NEUROTRANSMITTERS
& their Actions
• stimulates skeletal muscle
contraction (excitatory at
neuromuscular junctions)
• may be excitatory or
inhibitory at ANS synapses
ACETYLCHOLINE
MAJOR NEUROTRANSMITTERS
& their Actions
• generally inhibitory
GAMMA AMINOBUTYRIC ACID
MAJOR NEUROTRANSMITTERS
& their Actions
• may be excitatory or
inhibitory at ANS synapses
NOREPINEPHRINE
MAJOR NEUROTRANSMITTERS
& their Actions
• may be excitatory - active
during emotional responses,
addictive behaviors, &
pleasurable experiences
• may be inhibitory - help in
the regulation of skeletal
muscle tone and movement
DOPAMINE
MAJOR NEUROTRANSMITTERS
& their Actions
• generally inhibitory –
involved in control of mood
& onset of sleep
SEROTONIN
MAJOR NEUROTRANSMITTERS
& their Actions
• excitatory – involved in pain
perception
SUBSTANCE P
MAJOR NEUROTRANSMITTERS
& their Actions
• generally inhibitory – reduce
pain by inhibiting substance P
release
ENDORPHINS
MAJOR NEUROTRANSMITTERS
& their Actions
• inhibitory in PNS - promotes
vasodilation
NITRIC OXIDE