Nerve and Brain Lesions Flashcards
What are the nerve contents of most sensory nuclei?
Cell bodies of second order neurons
EXCEPTION: mesencephalic nucleus consists of cell bodies of first order neurons
Where are the cell bodies of most first order neurons for sensory cranial nerves?
Sensory ganglia of cranial nerves
Where do second order sensory neurons of cranial nerves usually synapse onto third order neurons?
Sensory nuclei of the thalamus (contralateral side)
Where are cell bodies of third order neurons for sensory cranial nerves?
Sensory relay nuclei of the thalamus
Where do axons of third order neurons in the sensory relay nuclei project?
To the primary sensory areas of the cerebral cortex (i.e. postcentral gyrus)
What is the effect of lesions of first order sensory neurons or the sensory nucleus? Lesions of the central pathway of sensory neurons?
First order/nucleus: ipsilateral sensory deficits (pre-decussation)
Central: contralateral sensory deficits (post-decussation)
Where do upper motor neurons synapse with lower motor neurons?
Motor nuclei
What is the most important upper motor neuron descending pathway?
Corticobulbar tract
What is the facial appearance of a lower motor neuron lesion in the brainstem or cranial nerves?
Ipsilateral flacid paralysis and loss of reflexes in full half of face
What is the facial appearance of an upper motor neuron lesion in the motor cortex and internal capsule?
Contralateral lower facial paralysis
contralateral because motor neurons for the lower half of the face cross, only lower because the upper face is supplied by neurons from both sides
What are the six cell columns of cranial nerve nuclei inthe spinal cord (listed medial to lateral)?
Somatic motor, parasympathetic, branchial motor, visceral sensory and taste, special sensory, and somatic sensory
What nerves are in the somatic motor column of the spinal cord?
- oculomotor nucleus (in midbrain at level of superior colliculus)
- trochlear nucleus (in midbrain at level of inferior colliculus)
- abducens nucleus (in midpons)
- hypoglossal nucleus (in medulla)
What nerves are in the parasympathetic column of the spinal cord?
Parasympathetic nerves from the oculomotor (Edinger-Westphal nucleus), facial (superior salivatory nucleus), glossopharyngeal (inferior salivatory nucleus), and vagus (dorsal motor nucleus) nerves
What nerves are in the branchial motor column in the spinal cord?
- trigeminal motor nucleus (rostral pons)
- facial motor nucleus (caudal pons)
- nucleus ambiguous (IX, X in the medulla)
- accessory nucleus (cervical cord)
What nerves are in the taste and visceral sensory column of the spinal cord?
Taste: rostral solitary or gustatory nucleus (VII, IX, X) in the medulla
Visceral sensory: caudal solitary nucleus (IX, X) in the medulla
What nerves are in the special sensory column of the spinal cord?
Vestibular and cochlear nuclei in the rostral medulla and caudal pons
What nerves are in the somatic sensory column of the spinal cord
What is the presentation of a hemisphere (supranuclear lesion)?
Interrupts both ascending and descending spinal and cranial nerve pathways –> body and face deficits contralateral to the injury