Nerve Flashcards

1
Q

Nerve fibers

A
  • axons enveloped by a sheath cell called a Schwann cell

- small axons usually unmyelinated and thicker are myelinated and have Schmidt-Lanterman clefts and nodes of Ranvier

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2
Q

unmyelinated fibers

A

-enclosed in a simple fold of a Schwann cell, some very thin can share a fold

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3
Q

Myelinated fibers

A
  • thicker axons
  • Schwann cell wraps around axon multiple times
  • squeezes out most of the cytoplasm except some places-schmidt-lanterman clefts
  • nodes of Ranvier indicate end of one Schwann and the beginning of another, which is covered by interdigitating processes
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4
Q

Nerves

A
  • bundles of fibers that contain myelinated and unmyelinated axons and motor and sensory fibers
  • surrounded by CT
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5
Q

epineurium

A
  • outermost layer
  • binds bundles or fascicles together into nerves
  • dense irregular to loose CT
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6
Q

perineurium

A
  • prominent layer, most visible
  • modified fibroblasts (epithelioid myofibroblasts)- form tight junctions with each other and collagen fibers
  • groups nerve fibers into bundles or fascicles
  • selective diffusion (blood-nerve) barrier
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7
Q

endoneurium

A

-delicate layer of reticular fibers produced by Schwann cells

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8
Q

ganglia

A
  • peripheral clusters of cell bodies of neurons that are surrounded by satellite cells
  • sensory and autonomic can be easily distinguished at the level of the light microscope
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9
Q

sensory ganglia

A
  • contain cell bodies of psuedonunipolar neurons
  • no synapses within ganglion
  • numerous myelinated fibers
  • neurons have a central nucleus and a regular ring of satellite cells-protective capsule
  • single cell process
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10
Q

pseudounipolar neuron

A

-oneish dendrite and cell body off to side of axon

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11
Q

bipolar neuron

A
  • 2 dendrites

- cell body in middle of axon

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12
Q

multipolar

A
  • multiple dendrites
  • cell body at top
  • one axon
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13
Q

autonomic ganglia

A
  • contain cell bodies of multipolar neurons
  • synapses in ganglion
  • numerous unmyelinated fibers
  • neurons have an acentric nucleus and smaller cell bodies
  • multiple cell processes, single axon
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14
Q

specialized termini

A
  • motor end plate
  • free endings
  • meissner’s corpuscles
  • pacinian corpuscles
  • muscle spindles
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15
Q

motor end plate

A
  • ending of motor neuron axons
  • synaptic vesicles at expanded axonal terminus
  • postsynaptic membrane has junctional folds and acetylcholine receptors
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16
Q

sensory receptors

A
  • externoreceptors
  • enteroreceptors
  • proprioreceptors
  • free endings
  • encapsulated endings
17
Q

free endings

A
  • bare axons are important for sensations from the skin of hot, cold, itching, touch, and pain
  • can go to a merkel cell?
18
Q

encapsulated endings

A

-meissners and pacinian corpuscles and muscle spindles

MERKEL??**

19
Q

Meissner’s Corpuscles

A
  • dermal papillae of hairless skin
  • 150 microns
  • touch receptors responsive to low frequency stimuli
20
Q

Pacinian Corpuscles

A
  • hypodermis and deeper dermis of skin
  • 1mm or larger
  • mechanoreceptors that respond to pressure and vibration
  • formed from concentric layers of Schwann cells
21
Q

Muscle Spindles

A
  • proprioceptor
  • encapsulated receptors in skeletal muscle
  • contain thin specialized muscle fibers called intrafusal fibers in a fluid filled space
  • sensory nerve fibers exiting the capsule send signals about the extrafusal muscle fiber length and relay this information to the spinal cord where it plays a role in reflexed involved in maintaining posture and coordinating walking