Nephrotic syndrome

Question 1

associated with minimal change

Answer 1

hodgkin lymphoma

Question 2

why is minimal change have excellent response to steroids

Answer 2

damage mediated by cytokines from T cells

Question 3

Focal segmental most common in

Answer 3

hispanics

african americans

Question 4

Focal segmental associated with

Answer 4

HIV
Heroin use
sickle cell dz

Question 5

mcc of nephrotic syndrome in caucasians

Answer 5

membranous nephropathy

Question 6

associated with membranous nephropathy

Answer 6

Hep B or C
solid tumors
SLE
Drugs - NSAIDs, penicillamine

Question 7

Membranoproliferative

Type I
associated with

Answer 7

HBV, HCV

Subendothelial

Question 8

Membranoproliferative

Type II
associated with

Answer 8

C3 nephritic factor

dense deposit - intramembranous

Question 9

characterize nephrotic syn due to DM

Answer 9

sclerosing of the mesangium with formation of kimmelstiel wilson nodules

microalbuminuria from hyperfiltration due to NEG of vascular BM – hyaline arteriolosclerosis in EFFERENT arteriole

Question 10

what slows hyperfiltration-induced damage in DM

Answer 10

ACE-I

Question 11

most common location for systemic amyloidosis involvement

Answer 11

kidney

Question 12

Where does amyloid deposit

Answer 12

mesangium

Question 13

membranous nephropathy immune complex deposits

Answer 13

subepithelial