"nephron isn't a word" Flashcards
medical renal disease typically __ the echogenicity of the kidneys bilaterally
increases
- brightness of cortex corresponds to severity but does not correlate to cause
+/- prominent pyramids
CHRONIC medical renal disease will typically cause size of kidneys to __
SHRINK
- end stage kds are small in size echogenic and often diff to find
function of kidney to remove waste products, excessive fluid, produce hormones, and regulate body’s __
salt, potassium and acid content
renal function to produce hormones ie -
stimulate RBC production
regulate blood sugar
control calcium metabolism
lab tests for renal function
serum creatinine
BUN
eGFR
serum creatinine __ when kidneys are not funcitoning properly
rises
**a waste product of muscle metabolism normally excreted in urine
BUN aka
blood urea nitrogen
urea waste product from protein metabolism formed in liver
nitrogenous wastes products of protein metabolism
BUN __ when kidneys are not functioning properly
rises
eGFR aka
estimated glomerular function
- calculation to assess how well renal glomeruli are filtering blood
- based on serum creatinine and age, sex, race
GFR <60 indicates
renal disease
GFR >60 indicates
normal funciton
GFR <15
renal failure
normal amount of urine output per day
1-2 L
AFR aka
acute renal failure
- develops over hours -weeks
CKD aka
chronic kidney disease
- develops over weeks - months
rapid decrease in renal function in previously stable chronic renal failure
acute on chronic renal failure
broad categories of renal failure
pre renal
*hypoperfusion
renal
* medical renal disease
post renal
* bilat obstruction
most common cause of acute renal failure
pre renal causes (not enough blood)
hypoperfusion
* shock
* dehydration
* hemorrhage
* heart failure
second most common cause for acute renal failure
medical renal disease
- something wrong with parenchyma of kidney
excessive nitrogenous products in blood
azotemia
increased BUN and serum creatinine
urine in your blood showing clinical symptoms
uremia
muscle weakness, cramping, cardiac arrhythmia, nausea/vomiting, shortness of breath
symptoms of azotemia
broad term referring to renal disorders that are tx with medical rather than sx therapy
medical renal disease
primarily involves parenchyma of kidney
“nephropathy”
common causes for nephropathy
acute tubular necrosis (ATN)
acute glomerulonephritis
**less common causes
acute cortical necrosis
amyloidosis
ATN aka
acute tubular necrosis
reversible if caught early because the tubules constantly regenerate
** common causes are toxic exposures or ischemic (hypotensive)
what is the most common cause for acute renal failure
ATN
agents for toxic ATN
drugs
- antibiotics
- antineoplastics
- anesthetics
chemicals
- carbon tetrachloride
-antifreeze (ethylene glycol)
pigments
- myoglobn (rhabdomyolysis)
- hemoglobin
xray contrast media
- “contrast nephropathy”
ESRD aka
end stage renal disease
unilateral small kidney; ddx??
vascular compromise
chronic infection
?is the other big ?hypertrophic compensation
**not medical renal disease
what is the most comon malignancy of the kidney
RCC
RCC loves __
to invade the renal vein and the IVC
RCC sono features
NO HYDRO
solid hypoechoic mass
+/- invasion of RV and IVC
TCC arises from __
urothelium
* kidney, ureter, bladder
frequently causes hydro
what is the most common benign tumour of the kidney
angiomyolipoma
sono features of angiomyolipoma
small, echogenic solid cortical mass
can be large, can hemorrhage
when multiple angiomyolipomata, what may this be associated with
tuberous sclerosis
which benign tumour causes excessive renin and can thus cause HTN
juxtaglomerular tumour
oncocytoma, adenoma and juxtaglomerular tumours are typically __
benign
**BUT STILL WORK THESE UP AS RRC CZ YOU CAN’T RELALY TELL THE DIFFERENCE SONOGRAPHICALLY
types of cystic tumours of the kidney
cystic RCC
multilocular cystic nephroma
ANGIOMYOLIPOMA AKA
RENAL HEMARTOMA
what is the angiomyolipoma made of
vessels
smooth muscle
fat
features of angiomyolipoma
usually solitary and unilateral
echogenic
in cortex, well defined
if small, typically asymptomatic
avascular
usually homogeneous
more common demographic for angiomyolipomata
female
renal hemartomas will demonstrate radio__ in CT
radioluscency
made up of fat so will come out DARK
atypical angiomyolipomas
ie exophytic
work up as possible RRC
CT cyst classification system aka
Bosniak rating (1-4)
renal adenoma vs. RCC
appear identical with u/s
typically <3cm
iso/hypo echoic solid parenchymal mass
** consider malignant until proven otherwise
which renal tumour is known for demonstrating a central stellate scar
oncocytoma
juxtaglomerular tumour aka
reninoma
produces renin
uncommon cause of primary HTN
sono features of reninoma
cortical lesion
<3cm
strongly echogenic
- ddx AML
malignant renal tumours
renal cell carcinoma
transitional cell carcinoma
renal lymphoma
nephroblatoma
RCC aka
renal cell carcinoma
hypernephroma
Grawitz tumour
renal cell adneocarcionoma
RCC demographic
more common in males
50-70 y
associated risks for RCC
smoking
ADPKD
acquired cystic kidney disease in end-stage (‘cysts of dialysis’)
con HIppel-Lindau disease
tuberous sclerosis
the “too late” triad of RCC clinical symptoms
hematuria (gross or micro)
flank pain
palpable mass
clinical symptoms for RCC
many asymptomatic; incidental
hematuria
flank pain
palpable mass
low grade fever
HTN
anorexia, fatigue, weight loss
sono appearance of RCC
solid, bulky parenchymal mass
variable echogenicity, usually iso/hypo
tend to invade renal vein
*check IVC
+/- punctate calc
+/- mets
HYDRO UNCOMMON
what features are indicative for malignancy regarding RCC
size
evidence of venous thrombus
evidence of metastatic adenopathy
evidence of liver mets
high velocity, low resistance Doppler
urothelial tumour of the renal pelvis
TCC
frequent complication of renal TCC
obstructive uropathy
*increased risk with smoking, exposure to certain chemicals like printing dyes
sono features and pitfalls for renal TCC
variable appearance
- hypoechoic solid mass in SINUS
HYDRO is common
pitfalls - clot; fungus ball
** check there is vascularity
Wilms tumour aka
nephroblastoma
tumour from metanephrogenic blastema cells; most common renal neoplasm in children
nephroblastoma
ddx of nephroblastoma
neuroblastoma (adrenal)
increased incidence of nephroblastoma in children with __ syndrome
Beckwith-Wiedemann syndrome
what type of spread causes metastases to kidneys
hematogenous spread
cancer of the lymphocytes
lymphone
Hodgkin and non-Hodgkin
what is the preferred technique for dx of lymphoma
CT
which type of lymphoma is the most concerning
non Hodgkin
Reed-Sternberg cells aka
B cells
- type of WBC
malignant mature B cells typically arizing in nodes of the neck, axilla and chest - typically occurring in young adults
Hodgkin lymphoma
cancer of B and T cells, can arise in lymph nodes or organs, more common in older people
non Hodgkin
enlarged PAINLESS nodes, fever/chills, unexplained weight loss, NIGHT SWEATS, lack of energy, pruritus
lymphoma symptoms
renal lymphoma usually associated with systemic __ lymphoma
non Hodgkin
*occasionally localized to kidneys
what are the sono appearances of renal lymphoma
focal pattern
* hypo, anechoic solid masses
diffuse pattern
* disruption of architecture, reniform shape
perirenal involvement
* hypo perirenal mass; perirenal “rind”
which renal condition can create a “rind” around the kidney
renal lymphoma with perirenal involvement
multilocular cystic nephroma aka
cystic RCC
encapsulared, multilocular cystic lesion
benign neoplasm
common demographic for cystic RCC
young males
older females
sono features of cystic RCC
complex cystic mass
unable to differentiate from malignant RCC
common pitfall for renal tumours
junctional parenchyma/ hypertrophied column of Bertin
** won’t alter contour
demographic for MCDK
obstetrics and pediatrics
non genetic congenital cystic kidney disease
little to no parenchyma
bilat enlarged kidneys with multiple cysts; with cysts in other organs
ADPKD
‘adult’ PKD
bilat enlarged echogenic kidneys in utero and pediatrics
ARPKD
cysts of dialysis aka
ACKD
acquired cystic kidney disease
**look for RCC
hydatic cysts aka
cysts within cysts
daughter cysts
water lily sign
multilocular cystic nephroma aka
cystic tumour
** younger males, older females
calyceal diverticula aka
milk of calcium cysts
cystic dilatation of the renal tubules within the pyramids; congenital disorder
medullary spone kidney
medullary sponge kidneys are prone to __
nephrocalcinosis and stones
cystic lesion with hx of trauma or intervention
think vascular complications
ie pseudoaneurysm
where do parapelvic cysts originate
renal sinus
what type of fluid is in a parapelvic cyst
lymphatic
sanguinous
bloody
t/f parapelvic cysts are usually bilateral
true
which plane of section may best help differentiate multiple marapelvic cysts from hydronephrosis
coronal
**want to demonstrate no communication
parapelvic cysts are __ cysts
lymphatic
parapelvic cysts have potential to cause __
HTN
hematuria
hydro
ACKD aka
acquired cystic kidney disease
‘cysts of dialysis’
uremic renal cystic disease
what kidney disease is seen in end stage kidneys; 90% of patients on dialysis for 5+ years
ACKD
ACKD increases risk for __
RCC 35x
associated with cerebral ‘berry’ aneurysms
ADPKD
renal hydatid cyst aka
Echinococcus granulosus
(tiny tape worm)
dominant inheritance = what percentage of occurrance in offspring
50%