Nephrology and Urology Flashcards

1
Q

What are the 4 characteristics of nephrotic syndrome?

A

proteinuria (>3.5 g/day)
hyperlipidemia
edema
hypoalbuminemia

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2
Q

What is the MC nephrotic syndrome in kids?

A

minimal change disease

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3
Q

What is the MC nephrotic syndrome in AA?

A

Focal Segmental Glomerularsclerosis

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4
Q

What is the MC nephrotic in caucasian adults?

A

membranous nephropathy

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5
Q

tx for minimal change disease?

A

corticosteroids

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6
Q

What is the gold standard to dx nephrotic?

A

24 hr urine collection

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7
Q

What are the hallmarks of acute glomerulonephritis?

A

HTN
hematuria (RBC casts)
dependent edema (proteinuria)
azotemia

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8
Q

What diseases only cause rapidly progressive glomerulonephritis?

A

vasculitis (Microscopic polyangiitis- pANCA, granulomatosis with polyagniitis- cANCA ie wegeners)

Goodpasture’s disease (lung and kidneys- hemoptysis)

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9
Q

What are the types of AKI?

A

prerenal**
intrarenal
postrenal

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10
Q

What is the MC type of AKI?

A

pre-renal

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11
Q

What is the MC type of intrarenal kidney injury?

A

acute tubular necrosis

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12
Q

Epithelial cell casts and muddy brown casts point to what?

A

intrinsic kidney injury- acute tubular necrosis

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13
Q

WBC casts point to what kidney problem?

A

intrinsic kidney injury- acute tubulointerstitial nephritis

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14
Q

RBC casts point to what kidney problem?

A

intrinsic kidney injury- glomerular (acute glomerulonephritis)

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15
Q

Hyaline casts point to what kidney problem?

A

nonspecific, can be normal

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16
Q

Fatty casts are seen in what kidney problem?

A

nephrotic syndrome

17
Q

What is pyuria MC due to?

18
Q

What heart problem is associated with polycystic kidney disease?

A

mitral valve prolapse

19
Q

Hyperparathyroidism causes a deficiency in what mineral?

A

phosphorus

20
Q

What is the MC cause of hyperphosphatemia?

A

renal failure

21
Q

What is the cut-off between microalbuminemia and macro?

A

300 mg/day

nephrotic is >3 g/d

22
Q

What are the common causes of renal disease?

A

DM
HTN
glomerulonephritis

23
Q

What is the best predictor of CKD?

A

proteinuria

24
Q

what is the preferred way to determine proteinuria in CKD?

A

spot UAlbumin/UCreatinine Ratio (ACR)

25
What cancer secretes ectopic ADH?
small cell lung cancer
26
How do you manage SIADH?
water restriction
27
What drug can cause nephrogenic diabetes insipidus?
lithium
28
Water homeostasis is governed by what hormone?
ADH
29
Na homeostasis is governed by what hormone?
aldosterone
30
what is normal serum osmolality?
285-295
31
What solutes are a part of the osmolality of the serum?
Na, glucose, BUN