Nephrology

Question 1

Side effect of cyclophoshamide

Answer 1

hemorrhagic cystitis

Question 2

Treatment for rhabdomyolsis

Answer 2

Bolus NS
Mannitol, diuresis
Alkalinization of the urine

Question 3

Goodpasture’s syndrome
Best initial test
Most accurate test
Treatment

Answer 3

Anti-basement membrane antibodies
Renal biopsy: “linear deposits”
Plasmapheresis, steroids

Question 4

Churg-Strauss syndrome
Best initial test
Most accurate test
Therapy

Answer 4

CBC for eosinophil count
biopsy
Glucocorticoids (prednisone), if no response then cyclophosphamide

Question 5

Wegener’s granulomatosis
Best initial test
Most accurate test
Therapy

Answer 5

C-ANCA
Biopsy
Cyclophosphamide and steroids

Question 6

Demeclocycline: what does it do?

Answer 6

Blocks effect of ADH at the kidney

Question 7

Conivaptan, Tolvaptan: what does it do?

Answer 7

Inhibitors of ADH

Question 8

Addison’s disease: Na, K

Answer 8

Hyponatremia

Hyperkalemia

Question 9

Conn’s Disease: Na, K

Answer 9

Hypernatremia

Hypokalemia

Question 10

Drugs that cause hypomagnesemia

Answer 10

Loop diuretics
Gentamicin
Cisplatin