Nephrology Flashcards
Which is larger afferent arteriole or efferent arteriole
Afferent arteriole
Normal urine protein excretion
Less than 150mg/ 24 hrs
Normal albumin excretion in urine
Less than 30mg/ 24 hrs
Microalbuminuria
30-300 mg/ 24 hrs
Macroalbuminuria
300-3500mg/ 24 hrs
Nephrotic range proteinuria
Albumin greater than 3500mg/ 24 hrs
Isolated proteinuria amount
Less than 2 grams / 24 hrs
Classification of pathological proteinuria
Mild = less than 500 mg
Moderate = 500 mg - 2 grams
Severe = greater than 2 grams
Pathological proteinuria according to nature
Selective
Non selective
Pathological protienuria according to site
Glomerular
Tubular
Overflow
Glomerular proteinuria
Increased capillary permeability (Glomerulonephritis)
Tubular proteinuria
Decreased tubular reabsorption of proteins (tubulo interstitial disease)
Overflow proteinuria
Increased production of low molecular weight proteins (Monoclonal gammopathies, leukemias, lymphomas)
Primary glomerular disease
Minimal change disease
Idiopathic membranous GN
Focal Segmented Glomerulonephritis
Membranoproliferative GN
IgA nephropathy
Secondary Glomerular Diseases
Diabetes
Connective tissue diseases like
Lupus Nephritis
Infection
Post streptococcal
Hep B
Malignancy
Lymphoma
Lung