Nephritic and Nephrotic Syndromes Flashcards
pneumonic for NEPHROTIC syndromes
Nephrotic=FM MAS
(Chris Evans has puffy eyes and he is on the radio)
List causes of nephrotic syndromes
-Focal Segmental Glomerulosclerosis
-Minimal change disease
-Membranoproliferative
glomerulonephropathy (can be either)
-Membranous
-Amyloidosis
-SLE Glomerulonephropathy
Typical nephrotic syndrome presentation
oedema (facial in sprogs, peripheral in adults)
frothy pish (protein)
immunodeficiency
arterial and vascular thrombosis (loss of antithrombotic proteins)
triad for diagnosis of nephrotic syndrome
proteinuria
hypalbuminaemia
oedema
Classic presentation of minimal change
2 year old, facial oedema
What is the most common nephrotic syndrome
minimal change peeyals
Cause of minimal change
Primary
Secondary (lymphoma, NSAIDs, allergy)
Management and prognosis of minimal change
Steroids!
Usually responsive, may relapse
Typical presentation of nephritic syndrome
red cell casts in pee pee
hypertension
oliguria
hypertension
(can get mild oedema and proteinuria too)
Child presents with oliguria, blood in pee and a strep infection two weeks ago…
What is the diagnosis
Post streptococcal glomerulonephritis
Typically post
is IgA nephropathy nephritic or nephrotic
nephritic
Key differences between IgA nephropathy and post-streptococcal glomerulonephritis
Time of onset after strep- PSGN 2 weeks
IgA nephropathy 1-2 days
Age- IgA in adults, PSGN kids
Typical presentation of IgA nephropathy
young adult (man)
1-2 days after strep infection
nephrotic-y presentation
pathology findings for minimal change disease
Fused podocytes on EM
(normal on light microscopy)
most common cause of glomerulonephritis in adults
Membranous glomerulonephritis
