Neoplasms: I-IV grading system, Gleason system, TNM System

Question 1

I-IV System aka

Answer 1

WHO classification

Question 2

I-IV System:

I

Answer 2

No spread beyond structure of origin

Question 3

I-IV System:

II

Answer 3

Spread into adjacent tissue

Question 4

I-IV System:

III

Answer 4

Spread beyond own region

Question 5

I-IV System:

IV

Answer 5

Involves another organ or distant site

Question 6

The Gleason System is a scale from and what do the numbers mean

Answer 6

A scale from 2-10

Lower number means a less aggressive tumor

Question 7

The Gleason System:

< 4

Answer 7

Less aggressive

Question 8

The Gleason System:

5-7

Answer 8

Intermediate

Question 9

The Gleason System:

8-10

Answer 9

Fast growing tumors

Question 10

TNM system:

TNM is an acronym for

Answer 10

T – Tumor size

N – Nodes

M - Metastasis

(will see this system most often)

Question 11

TNM system:

T0

Answer 11

No evidence of 1° tumor

Question 12

TNM system:

T1

Answer 12

Tumor only verifiable via bx (can’t see on imaging)

Question 13

TNM system:

T2

Answer 13

Tumor confined to the site of origin

Question 14

TNM system:

T3

Answer 14

Tumor has spread slightly outside of the site of origin

Question 15

TNM system:

T4

Answer 15

Tumor has spread to other parts of the body close to the site of origin or more distant parts

Question 16

TNM system:

N0

Answer 16

Tumor has not spread to nodes

Question 17

TNM system:

N1

Answer 17

Tumor has spread to the closest or only small # of regional lymph nodes

Question 18

TNM system:

N2

Answer 18

Tumor has spread to extent btw N1 & N3

Question 19

TNM system:

N3

Answer 19

Tumor has spread to most distant or numerous regional lymph nodes

Question 20

TNM system:

M0

Answer 20

Tumor has not metastasized

Question 21

TNM system:

M1

Answer 21

Tumor has spread to other parts of the body (beyond regional lymph nodes)