Hypofysenadenom - Prolaktinom - Somatotrop - ACTH-secernerende

Neoplasier oversigt Flashcards by Daniel Aastrup

Tyndtarm

Malign neoplasi

Karcinoid tumor i appendix

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Bløddele:

1) Benign
2) Malign

1) Lipom, intramuskulært myksom, fibrom, rhadomyom, leiomyom

2) Fibrosarkom, rhabdomyosarkom, leiomyosarkom

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Blære:

Malign tumor

Blæretumor

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Thymus:

1) Benign
2) Malign

Thymom

Thymuskarcinom

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Uterus:

1) Præmalign
2) Benign
3) Malign

1) Endometriehyperplasi
2) Endometriepolyp, uterusleiomyom
3) Endometriekarcinom

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Ovarie

1) Inddeling af overfladederiverede
2) Benign
3) Malign

1) Benign, borderline(CIS) og malign
2) Brenners tumor, Serøse(65% benign), mucinøse(75% benign)
3) Endometroid

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Brystet:

1) Præmalign
2) Benign
3) Malign

1) Paget’s disease of the nipple
2) Fibroadenom, Intraduktal papillom, Phyllodestumor
3) DCIS, LCIS, Duktalt karcinom(75%), lobulært karcinom(10%)

5000 tilfælde årligt
BRCA-1 og -2
HER-2 og østrogenreceptor

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Spytkirtler:

1) Benign
2) Malign

1) Pleomorft adenom, Warthins tumor

2) Adenoidcystisk karcinom, mukoepidermoidt karcinom

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Pancreas:

Malign neoplasi

Adenokarcinoma pancreatis

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Colon og rectum:

1) Benign neoplasi
2) Malign neoplasi
3) Særlige mutationer

1) Kolerektal adenom
2) Kolorektal karcinom, HNPCC, FAP
3) Lynch, BRAF

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Angiv for øsofagus:

1) Præmaligne forandringer
2) Maligne neoplasier

1) Barret’s

2) –> øsofagus karcinom

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Hypofysen:

Benign

Hypofysenadenom

Prolaktinom
Somatotrop
ACTH-secernerende

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Knoglemarv

Læs i bogen

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Knogle:

1) Benign
2) Malign

1) Kondroblastom(drenge), osteoidt osteom, (en)kondrom, osteoklastom
2) Kondrosarkom, osteosarkom, Ewings sarkom, metastaser

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Pharynx:

1) Benign
2) Malign

1) Juvenilt angiofibrom

2) Nasopharyngealt karcinom(EBV), oropharynxkarcinom(HPV)

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Angiv for hjertet:

Benign neoplasi

Myksom

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Hud:

1) Præmalign
2) Benign
3) Malign

1) Aktinisk keratose, Mb. Bowen(planocellulært carcinoma in situ)
2) Fibroepithelial polyp, planocellulært papillom, keratokantom, lentigo, melanocytær nævus, spitz nævus(hos børn)

3)  
Basecellulært karcinom ---> planocellulært
   -klassisk nodulær
   -superficielle 
   -infiltrerende
Malignt melanom
    -lentigiøst akralt(hænder og fødder)
    -superficielt spredende(75%)
    -nodulær
   -lentigo maligna melanoma(ansigtet hos gamle)

Binyre:

1) Benign
2) Malign

1) Adenom, fæokromocytom

2) karcinom, neuroblastom

Ovarie

1) Germinalcelletumorer
2) Sex cord-stroma tumor

1) Teratom, koriocarcinom, blommesækstumor, embryonalcelle tumor
2) Granulosacelletumor(østrogen konvertion), tekom(de novo østrogen)

Larynx:

1) Præmalign
2) Benign
3) Malign

1) Leukoplaki
2) Papillom
3)
Larynx planocellulært karcinom
-Supraglottis(30%)
-Glottis(65%)
-Subglottis(<5%)

Lever:

1) Benign neoplasi
2) Malign neoplasi

1) Hæmangiom, hepatocellulært adenom

2) Hepatocellulært karcinom, kolangiocellulært karcinom, angiosarkom, hepatoblastom(børn), og metastaser

Angiv for ventriklen:

Malign neoplasi og spredning

Ventrikelkarcinom
Gastrointestinal stromal tumor(GIST)
-Behandling: Tyrosinkinase inhibitor
Malignt lymfom

Spredning:
Omkringliggende væv og hæmatogent

Lymfeknude:

Plasmaceller

Myelomatose(osteolytisk)

Lunge

1) Benign
2) Malign

1) Hamartom, kondrom

2) 
Mesotheliom: asbest
Cancer:
   -planocellulært
   -adenocarcinom
   -småcellet
   -storcellet
   -neuroendokrint
   -karcinoid
   -atypisk karconoid

Tuba uterina: | Malign

Karcinom

Cervix uteri: 1) Præmalign 2) Malign

1) Dysplastiske forandringer | 2) Carcinoma

Prostata: | Malign tumor

Adenokarcinom i prostata

Cavum oris 1) Benign 2) Præmalignt 3) Malign

1) Planocellulært papillom 2) Leukoplaki 3) Planocellulært carcinom

CNS: | Malign

``` Gliaceller: -Astrocytom -Oligodendrogliom -Ependymom Primitiv neuroektoderm celle: -Medulloblastom Araknoidalcelle: -Menigeom Nerveskedecelle: -Schwannom -Neurofibrom ```

Næse: 1) Benign 2) Malign

1) Planocellulært papillom, kapillært hæmangiom, Schneiders papillom(HPV) 2) Sinonasale karcinomer -planocellulært karcinom -adenokarcinom

Lymfekunder: | -Hodgkins

Lymfocyt-prædominant(10%) Klassisk Hodgkins(90%) - Nodulær skleroserende - Lymfocytrig-klassisk - Mixed cellularity - Lymfocytdepletion

Nyre: 1) Benign neoplasi 2) Malign neoplasi

1) Adenom, onkocytom | 2) Nyrepelvistumor, renalcellekarcinom(hyppigst), Wilm's tumor(børn), metastaser

Thyroidea: 1) Benign 2) Malign

1) Thyroideaadenom 2) Thyroideakarcinom - papillært, follikulært, medullært(C-cellederiveret), anaplastisk BRAF mutation

Testis: | Malign

Germinalcelletumorer (95 %) - Seminom - Teratom - Embryonalt karcinom - Koriokarcinomet Non-germinalcelletumor - Leydigcelletumor - Sertolicelletumor

Anus: Malign neoplasi Spredning

Planocellulært karcinom | Spredes hæmatogent til lever og lymfogent til lymfeknuder i inguinalkanalen

Lymfeknuder: | B-celle

Precursor: -Akut lymfoblastær leukæmi(B-ALL) (hos børn) Mature: - Kronisk lymfocytær leukæmi - (CLL) - Småcellet lymfocytært lymfom (SLL) - Follikulært lymfom (FL) - Diffust storcellet B-celle-lymfom (25%) - Burkitts lymfom (BL)(HIV og EBV)

Lymfeknuder: | T-celle

Precursor: -Akut lymfoblastær lymfom(T-LBL) Mature: - Perifært T-celle- lymfom - Mycus fungicides (MF)

Galdeblære: | Malign neoplasi

Galdeblærecancer(højmalign)

Parathyroidea: 1) Benign 2) Malign

1) Adenom | 2) Karcinom

Penis: 1) Præmalign forandringer 2) Benign 3) Malign

1) Mb. Bowen, Carcinoma in situ 2) Kondylom 3) Planocellulært karcinom Skyldes HPV 6 og 11