Neoplasia Flashcards
Tumor means
swelling, refers to mass (usually neoplastic)
Neoplasia
excessive autonomous growth
Hyperplasia
increase in cell number
Metaplasia
change from one cell type to another
Dysplasia
disordered cell growth
*used for preneoplastic epithelial proliferation
Anaplasia
lack of cell differentiation
Neoplasia
excessive, autonomous growth
Normal hyperplasia example
breast growth during pregnancy, nursing
Metaplasia classic example
Barrett’s esophagus–intestinal metaplasia of esophagus lining
Preneoplastic epithelial proliferation is
a Dysplasia.
microscopically–cytologic and architectural abnormalites
Reversible
Dysplasia can also mean
non-neoplastic growth abnormality
non-neoplastic growth abnormality, examples:
renal dysplasia
hip dysplasia
Big difference between Metaplasia vs Dysplasia
Metaplasia–reactive process, not pre-neoplastic
Dysplasia-pre-neoplastic
Neoplasia (breast) Benign
Fibroadenoma
Neoplasia (breast) malignant
adenocarcinoma
Neoplasia (anaplasia) is not
reversible
3 traits of neoplastic cell growth
autonomous
excessive,
disorganized
Benign tumor cells remain at site of origin and grow as a ____
encapsulated mass
to name a benign tumor
add suffix -oma
to name a malignant tumor
eptithelial—carcinoma
mesenchymal–sarcoma
mesenchymal origin tissues
adipose, cartilage, muscle
epithelial origin tissues
gland, squamous
papilloma is ?
benign
adenoma is ?
benign
melanoma
malignant, melanosarcoma
seminoma
malignant, testicular cell carcinoma
lymphoma
malignant, lymphosarcoma
leukemia
malignant, lymphosarcoma
hepatoma
malignant, hepatocellular carcinoma
Tumor ___ has more predictive value than ___
staging / grading
