Neoplasia

Question 1

Lack of differentiation of cells, which resenbles more primitive cells of similar tissue

Answer 1

Anaplasia

Question 2

Pleomorphism, hyperchromatism, increased N:C ratio (normal 1:4 and malignancy 1:1)

Answer 2

Dysplasia

Notice: NO abnormal mitoses

Question 3

Pleomorphism, hyperchromatism, increased N:C ratio (normal 1:4 and malignancy 1:1) and abnormal mitoses

Answer 3

Anaplasia

Question 4

Papilloma
Squamous cell papilloma
Adenoma
Liver cell adenoma

Answer 4

Benign tumor - epithelium

Question 5

Hemangiosarcoma
Lymphangiosarcoma
Leiomyosarcoma
Rhabdomyosarcoma
Fibrosarcoma
Liposarcoma
Osteosarcoma

Answer 5

Malignant tumor - mesenchymal

Question 6

Fibroma
Lipoma
Osteoma
Hemangioma
Lymphangioma
Leiomyoma
Rhabdomyoma
Cytadenoma

Answer 6

Benign - mesenchymal tissue

Question 7

Squamous cell carcinoma
Adenoma
Hepatoma
Transitional Cell carcinoma
Melanoma

Answer 7

Malignant - epithelium

Question 8

Major characteristic of malignancy

Answer 8

Anaplasia

Question 9

Hallmark of malignant tumor

Answer 9

Metastais

Question 10

What are the differences in the structure of benign and malignant tumors?

Answer 10

Benign - very well differentiated

Malignant - varying degrees of imperfect differentiation

Question 11

What are the differences in the mode of growth of benign and malignant tumors?

Answer 11

Benign - expansile growth, compression, capsule

Malignant- invasional growth, no capsule, infiltrate other tissues

Question 12

What are the differences in the rate of growth of benign and malignant tumors?

Answer 12

benign - slow growing, scanty mitoses, mitotic figures are normal
Malignant - rapidly growing with numerous and abnormal mitoses

Question 13

Do benign tumors ever matastasize?

Answer 13

NO - never

Question 14

What are two exceptions of malignant tumors that never matastasize?

Answer 14

Glioblastoma multiforme of CNS

Basal cell carcinoma of skin