Neoplasia Flashcards
What protein helps prevent cancer?
P53 proteins check check if cells look like their parent cells and kills any that doesn’t
How does cancer disrupt our bodys checks and balances to monitor for cancer?
Kills P53 genes
T or F: tumors often create their own vascular supply
True
MC way cancer spreads
thru blood
Others: direct tissue to tissue spread, lymph spread, transplant of tumor cells (iatrogenic)
Is tumor staging based on clinical signs or biopsy reports?
biopsy report
Ways to biopsy
- fine-needle/core bx
- Exfoliative (pap smear)
- Brushings/washings (bronchial specimens)
- Incisional bx - rmv part of it (some bad tissue remains)
- Excisional bx - rmv it all + some healthy tissue (To eval borders)
tissue source and feature
Adenoma
tissue source and feature
Lipoma
tissue source and feature
Leiomyoma
tissue source and feature
Fibroma
tissue source and feature
Hemangioma
Do Sarcomas come from ectoderm, mesoderm, or endoderm?
mesoderm
Sarcomas develop in bone, fat, MUSCLE, etc
Benign esophageal tumors
Papilloma
Adenoma
Leiomyoma
Granular Cell Tumor
Fibrovascular Polyps
Hamartoma
Lipoma
Malignant Esophageal tumors
SCC
Adenocarcinoma
MC benign esophageal tumor
Leiomyoma
Benign esophageal tumor commonly seen with barret’s esophagus
Adenoma
Benign esophageal tumor located in the head/neck region and is associated with eosinophilic esophagitis
Granular Cell Tumor
Are benign or malignant esophageal tumors more common?
Malignant
Malig esoph tumors
Is SCC or Adenocarcinoma more common?
SCC
Smoking and ETOH puts you at higher risk for
A. SCC
B. Adenocarcinoma
SCC
High BMI and GERD puts you at higher risk for
A. SCC
B. Adenocarcinoma
Adenocarcinoma
study of choice for esophageal tumor
Endoscopy + Bx
Endoscopy of malignant esoph tumor shows metastic dz. Order a _______
PET Scan to eval metastases in more detail
Trmnt for esophageal SCC?
Chemo
Trmnt for Esophageal Adenocarcinoma?
Sx + Chemo
Benign gastric tumors
Hyperplastic Polyps
Fundic Gland Polyps
Gastric Adenomas
Inflamatory Fibroid Polyps
Gastric Neuroendocrine Tumors
MC malig gastric tumor?
Adenocarcinoma